Jon Ryan had lived long enough to know better. But with age does not automatically come wisdom. He has saved mankind many times. He even resurrected Earth and all its inhabitants from never-having-existed. But he's still haunted, and haunted people do crazy things.

Charlie Travers figures his life can’t get much worse. He lives over a pizza restaurant, he’s lost his girlfriend, and has no prospects for a career. Then, he’s abducted by an alien robot and taken across the galaxy. When he wakes up, he finds himself stranded thousands of light-years away, and about to be killed by space pirates.

During a test flight for the world’s first warp engine, Major Noah Gantz is set to go down in the history books. Despite years of training, the mission goes sideways, and instead of a quick trip to the moon and back, Noah's ship is transported across the universe to stars unknown.

We were fighting on the wrong side of a war we couldn't win. And that was the good news. The Ruhar hit us on Columbus Day. There we were, innocently drifting along the cosmos on our little blue marble, like the native Americans in 1492. Over the horizon come ships of a technologically advanced, aggressive culture, and BAM! There go the good old days, when humans only got killed by each other. So, Columbus Day. It fits. When the morning sky twinkled again, this time with Kristang starships jumping in to hammer the Ruhar, we thought we were saved.

The world’s food supply grows aggressively, occupying every inch of earth, no matter how inhospitable. World hunger is averted. Humanity flourishes. RC-714 is digested, absorbed…and passed on. The Change affects small fast-breeding mammals first. They multiply with the same aggressive speed as the ExoGen plants, but an insatiable hunger drives them to violence. A war between species breaks out. When RC-714 reaches humanity, along with every other large creature on the planet, civilization implodes.