A lorry crashes on a dark, wet road. In the wake of the tragedy, a dying man receives another chance at life - but does he really deserve it? And if he lives, will those around him wish he hadn't? When critically ill Jacob Wilson has a heart transplant, his behaviour becomes very strange. His worried parents and girlfriend try their best to understand his sudden mood swings, but as things worsen, they begin to live in terror of what they might find in their son's bedroom next - and as Jacob's personality morphs, so, too, do the lives of those around him....

After ten years, Sarah and her husband Roshan are looking forward to catching up with their closest school friends. So when one of them invites the group to spend a week in a beautiful converted church, they eagerly accept. Very quickly though, Sarah becomes unsettled. She is frightened by the church’s creepy surroundings, and she thinks she might be seeing ghosts. Even more disturbing, a masked woman is committing armed robberies in the area – and the police can’t catch her.

When Emily and Ben move in next door to Dr Burman and his wife, Anita, they are keen to get to know their new neighbours. Outgoing and sociable, Emily tries to befriend the doctor’s wife, but Anita is strangely subdued, barely leaving the house, and terrified of answering the phone. When Emily goes missing a few weeks later, Ben is plunged into a panic. His wife has left him a note, but can she really have abandoned him for another man? Or has Emily’s curiosity about the couple next door led her straight into danger?

Eight-year-old Leila Smith has seen and heard things that no child should ever have to. On the Hawthorn Estate, where she lives, she often stays out in the playground long after the other children have left, just so she can avoid her own home for longer. But what Leila doesn't know is that someone has been watching her. One day, she disappears without a trace. The police search start a nationwide search, but it's as if Leila has vanished into thin air. Who kidnapped her? What do they want? Will she return home safe and sound, or is she lost forever?

Damian is just seven when he is taken in by foster carer Cathy Glass. His mother, Rachel, loves her three young children dearly, but she is vulnerable, naïve and unable to cope on her own. Cathy sets about helping Damian overcome his eating issues, with the hope that he will eventually return home. But when Rachel’s new boyfriend, Troy, arrives on the scene, Cathy becomes deeply concerned. She soon realises that Damian and his siblings are in great danger.

Three-year-old Lexie, five-year-old Amelie and thirteen-year-old Leo come to Maggie after Leo confesses to a teacher that his mother's addiction problems and her latest violent relationship has left him as the sole carer to his younger sisters. Maggie welcomes the three children into her home and is touched by the gentle care Leo shows to the two little girls. It is clear that Lexie and Amelie adore their big brother and rely on him for comfort and reassurance.

Three siblings arrive at Maggie's door after being taken into care. Teachers of eight-year-old Bobby spotted bruises while he was getting changed for PE and his dad, Lee, and stepmother, Brianna, have been uncooperative and hostile to Social Services. While they investigate, Bobby, as well as Brianna's daughters, Melodie and Poppy, are all placed in Maggie's care. But as the children settle in, a thought won't let Maggie go. While Melodie and Poppy are clean, well-fed and immaculately dressed, Bobby is pale, severely underweight and crawling with lice.

After a horrific car crash, two parents are left dead, and a young girl is fighting for her life in hospital. When 13-year-old Louisa wakes to find that her loving, happy family has been shattered overnight, she is forced to seek comfort in the arms of a stranger. But can Maggie find a way to bond with this teenager overwhelmed with anger and grief? And will she regret making a decision that will affect her and Louisa for the rest of their lives?

Nina can never forgive Maggie for what she did. And she can never let her leave. They say every house has its secrets, and the house that Maggie and Nina have shared for so long is no different. Except that these secrets are not buried in the past. Every other night, Maggie and Nina have dinner together. When they are finished, Nina helps Maggie back to her room in the attic, and into the heavy chain that keeps her there. 

Named after the lager that christened her at birth, Stella's life is characterised instability and neglect. Her teenage mother abandons her in the first few weeks of her life, and left in the 'care' of her father, she ends up lying deserted in a house with no food, no water, no clothes and no warmth. She eventually lands in the care of foster carer Louise, who is determined to change her life for the better.