Andrew McCarthy grows concerned for his family after he catches a young man, Zachary Denton, photographing his daughter, Grace McCarthy, and other children at a park. To his dismay, Zachary talks his way out of trouble when he’s confronted by the police. He hopes that’s the end of it. Then he finds Zachary at a diner and then at a grocery store. He knows their encounters aren't coincidences. And just as Andrew prepares to defend his family, Grace vanishes. 

No one saw it coming. It started with isolated reports of people kidnapping babies and blending them to drink their "essence"—a highly potent and highly addictive chemical compound found in infants. The phenomenon spread through social media, infecting other addicts. Cases of kidnapping and murder—femicide and infanticide—skyrocketed, leading to governments around the world to issue state of emergencies and strict shelter-at-home orders.

Six strangers arrive at the home of preeminent puzzle master Alexei Vasiliev for the reading of his will. Among them are the deceased's widow, who'd already begun divorce proceedings, a virologist troubled by actions in his past, and a convicted murderer on day release. The potential beneficiaries will split Vasiliev's $150M fortune if they participate in his last great work. The choice is simple: leave the house with nothing or continue in the hope of solving the six interconnecting escape rooms within this house.

Mia and Finn are busy turning a derelict house into their dream home when Mia unexpectedly falls pregnant. But just when they think the house is ready, Mia discovers a shocking message scored into a skirting board: I WILL SAVE THEM FROM THE ATTIC. Following the clue up into the eaves, the couple make a gruesome discovery: their home was once a real-life murder house, with the evidence still concealed within the four walls.

The Lonely Motel holds many dark secrets and room six just might hold the worst of them all. Angel knows a lot about pain. His mother died in this room. He's researched its history. He's come back today to end it, no matter the cost, once and for all. Prostitute Shyla believes the stories Angel tells her can't be true. Secrets so vile, you won't want to let them inside you. But the Lonely Motel doesn't forget. It doesn't forgive. And it always claims its victim.