Dr. Carrie Markham’s heart was broken by the death of her husband two years ago. Now, just as her medical practice is taking off, her engagement to paralegal Adam Davidson seems almost too good to be true . . . until a drive-by shooting leaves Carrie on the floor of his car with glass falling around her. When he confesses that Adam isn’t his real name and that he fled the witness protection program, Carrie is left with an impossible choice: should she abandon the fiancé she isn’t sure she knows, or accept his claim of innocence and help him fight back against a faceless menace?

Dr. Ben Merrick and his fiancé, Rachel Gardner, can't get her divorced parents to stay in the same room, much less attend their wedding together. He is already looking over his shoulder expecting more trouble from a very senior surgeon who has shown he is still smarting from a previous dust-up, but Ben doesn't know if a series of mishaps and accidents are caused by a disgruntled patient's relatives or represent more from the older surgeon. Complicating it all is the question of whether Rachel's father is back doing drugs.

For Dr. Cathy Sewell, Code Blue means more than just the cardiac emergencies she faces - it's the state of her life when the return to her hometown doesn't bring the peace she so desperately needs. The town doctors resent the fact that she's not only a newcomer but also a woman, and the devastating results from one of her prescriptions may mean the end of her practice. As two men compete for her affection, an enemy wants her out of town - or possibly even dead.

When her phone rang, Diane Macklin wondered what her sister wanted now. Then she heard that their mother was in the emergency room with a heart problem. The doctor tending to her mother was Dr. Joe Adams, who was far from Diane’s idea of the family doctor. He had been alone since his first wife had died, and was apparently heaven-sent as a mate for Diane, if she could only get past the trauma of her previous near-miss at the altar. The heart problem was hard to solve initially, but the subsequent difficulty turned out to be murder, and affected the lives of both Diane and Joe.

Things were going along just fine. Until the miracle fouled them up. Three individuals become linked to the other, and each finds that God has a purpose for them - but, as it often does, the lesson comes with discomfort. 

The box contained a cell phone, which rang as soon as she opened the package. A voice that called Dr. Kathy Hoover by name said that her husband had been kidnapped. To get him back, she would have to poison one of her patients. At first, she didn’t believe that her husband had been taken from the conference he was attending, but soon she discovered that the kidnappers really had Darren. If she wanted to see him again, she had to give medication that would murder Kelton Rush, former Vice-President. What was she to do? How would she handle this critical decision?

Dr. Jacey Flanigan has worked tirelessly to achieve her dream of becoming a pediatric cardiologist. But when she moves to Manhattan to begin her career at a prestigious children's hospital, she discovers that the medical profession may not be what she expected. An encounter with an arrogant heart surgeon on her first day sets the tone for what's to come - a world of enigmatic physician behavior and questionable cardiac surgical practices cloaked in secrecy.

When Dr. Caden Taggart saw the two men sitting in his waiting room, he didn’t think they were patients. He was right, and when they introduced themselves as agents of the Drug Enforcement Agency, things started to get bad. Then Caden felt as though someone had gut-punched him when his father, Dr. Henry Taggart, told him he probably had carcinoma of the pancreas. When he talked about his son assisting with his suicide, Caden wondered how he could talk him out of that.

The colored lights on the snow gave it a holiday appearance, but the dead woman's body in the yard added a grisly touch. How did Ina Bell Patrick die? Who killed her? And why? The dead woman had no direct heirs, so two nephews and a niece stood to inherit. Dr. Laura Morris was left to make all the arrangements, attorney Roger Morris could certainly use the money, and Zack Morris had disappeared two years earlier.

Dr. Kelly Irving knew her husband, attorney Jack Harbaugh, was acting strangely but figured they’d get through it. When she backed out of her garage that morning, she thought her car hit a bump. Instead, its progress was stopped by the body of a man her husband recently represented. The dead man had been shot by her husband’s gun. Jack was a primary suspect. Kelly couldn’t decide if Jack was a murderer or marked as the next victim. They were forced to put their marital differences aside and concentrate on keeping Jack alive while discovering who was behind the whole thing. 

Dr. Jack Wyatt is renowned for solving the unsolvable. When a colleague approaches him about a dangerous new malady affecting only Leukemia patients at a prestigious oncology hospital, the mysterious case is too intriguing to pass up. So he and the brilliant Dr. Madison Shaw, a physician who shares not only his expertise but also his devotion to medicine, embark in a race against time to save the children as cases mount. Within the hospital walls, they confront a labyrinth of medical conundrums, hostile colleagues guarding their territory, and a web of political intrigue.

Running away from a past she’d rather forget, Doctor Alison Wilson has moved to a new town to take up the role of Medical Officer at failing hospital St Margaret’s. Tasked with shaking things up, she quickly learns that things are worse than they initially seem: patient records are in disarray, staff morale is low, and there’s something afoot that she can’t quite put her finger on As Alison starts to dig into the hospital’s past, she gradually discovers a trail of lies that runs deeper and darker than she could have ever imagined.

Detective James Holton has been honorably discharged from the Army Criminal Investigation Division due to wounds sustained when an IED blew up near him. Now with the Lake City Police Department, he's rooming with his good buddy and partner, Cole, while he figures out his family dynamics. Physician Assistant Lainie Jackson is eighteen months out from an attempted murder perpetrated by her ex, which ended when she managed to grab the weapon and shoot him. When he appears to have survived and is back to finish the job he started, Lainie insists it's not possible.

EMS helicopter pilot Penny Carlton is used to high stress situations, but being forced to land on a mountain in a raging storm with a critical patient - and a serial killer on the loose - tests her skills and her nerve to the limit. She survives with FBI Special Agent Holt Satterfield's help. But she's not out of the woods yet.

Whether it's poker or trial law, wisecracking Rita Morrone plays to win, especially when she takes on the defense of the Honorable Fiske Hamilton, a prominent federal judge accused of sexual harassment. And it's no coincidence that the judge is her live-in lover's father. Then the action turns deadly, and Rita finds herself at the center of a murder case. She probes deep into the murder, uncovering a secret life and suspects in shocking places.