No evildoers have tried to flatten Peter Parker in weeks. His marriage to Mary Jane is stronger than ever, and he's enjoying his job as a high-school science teacher. Life is good. Naturally, that doesn't last. When Peter learns that his old enemy, the Rhino, is on a rampage in Times Square, he suits up as Spider-Man to stop the destructive villain in his tracks. But he's unexpectedly foiled in his attempts by the Black Cat, a former ally and old flame. The Cat informs Peter that the Rhino is just a distraction - the real threat comes from a group of Ancients.

Miles Morales has a lot going on, what with moving to a new neighborhood, dealing with the loss of his father, and the whole gaining superpowers thing. After a misunderstanding with the law, Miles questions what it means to be a hero when people are ready to believe the worst of you. Tempted by the power and freedom of his new abilities, Miles must decide what kind of Spider-Man he wants to be. When Vulture starts wreaking havoc across the city with his new accomplice Starling, Miles can't just sit back and watch.

In a Manhattan warehouse, an innocent man has been murdered during a mysterious crime. Evidence points to the involvement of Venom - the alien symbiote obsessed with Spider-Man's destruction. Yet Venom has always safeguarded innocent lives. Has Venom gone completely around the bend, or is there another suspect? Spider-Man thinks there is more to the crime than meets the eye. The specter of the Hobgoblin, one of Spider-Man's nastiest foes, falls on a series of thefts and leads the web-slinger to a deadly secret that may cause New York's destruction.

The sequel to The Present and the conclusion of the Time's Arrow trilogy narrates the struggle of the X-Men and Spider-Man to stop the time-traveling madman Kang the Conqueror from destroying the multiverse and time as they know it.

Peter Parker is caught in a complicated web. Working in a cutting-edge laboratory, he's a young scientist who's trying to make a difference. Yet he's constantly burdened by the responsibilities of his second career as the crime-fighting Spider-Man. Wilson Fisk - the so-called Kingpin of Crime - has returned to New York, establishing himself publicly as an altruistic entrepreneur and philanthropist. Spider-Man knows better, but he can't uncover Fisk's scheme, which, if executed, will make the crime lord too big to fail.