Ellie Fisher loves most things about being a nurse in the emergency department . . . just not working with Regina Novak, an icy attending physician who acts as if she's God's gift to medicine. The dislike is completely mutual. Regina thinks Ellie is a starry-eyed romantic with a sentimental attitude that has no place at work. When Regina gets talked into volunteering at a singles auction, Ellie accidentally bids on her—and ends up winning. Oops! Since the money raised is for a good cause, they reluctantly decide to go through with the dates.

When professional soccer player Alex Grey goes on a vacation to the local South Carolina islands, she isn't anticipating any life-changing events. Just a relaxing weekend to prepare for the upcoming season. But that quickly changes when she finds herself the lone witness to a sailing accident and makes the decision to risk her own life to save a drowning woman—unwittingly coming to the rescue of a US senator's wife, Catharine Cleveland.

Six months ago, Ty Sutherland dropped out of an online sex chat group. It was anonymous. No one knew their real identity. And it was a space where they could finally be themselves. Unfortunately, it was also a space where they fell in love with a woman whose name they promised to forget. Leslie Brandt would like to forget the online sex chat group she joined on a whim. In real life, she's a successful realtor with a professional image to maintain. She'd never want anyone to know the kinky things she's fantasized about—even if maybe she wishes some of those things could actually happen.

Since A-List actress and Hollywood's sweetheart Wren Acker came out, not only is she at the top of the acting world; she's also crush number one for her queer fanbase. Loving life, loving her job, loving her cat-everything is fantastic. Except that lack of any kind of private life. When a car accident brings her to the ER, the bottom falls out of her world when she realizes that reserved Doctor Taylor, her physician, is Madison Taylor from camp way back when she was a kid. And boy, does Madison still hold a well-earned grudge for how that all ended.

It’s an ordinary workday when intelligence analyst Lexie Martin learns about a horrific chemical weapon attack abroad. Just an ordinary day...until a stranger breaks into her house and warns her to forget what she saw and heard, setting off a chain of events Lexie thought only happened in movies. Falsely accused of stealing intelligence and unsure of who to trust, Lexie quickly realizes the significance of the intel and that she must do everything she can to keep it safe. And as she runs—maybe for her life—Lexie knows she needs something, or someone, to help her.

Ren Dunbar is used to never fitting in—anywhere. Graduating high school at 13 and med school at 19 pretty much guaranteed she’d always have trouble proving she belonged, but she’s okay with that. She prefers the solitude of the lab over the raucous atmosphere in the OR, which would be fine except she’s a surgery resident. Winning the Benjamin Franklin Prize in surgery is just the proof she needs to show everyone she deserves to be part of their world. 

Dr. Jillian Byers only considered two careers: indie rock sensation or physician. Both dreams led her to Los Angeles. She never plotted a course that led back home. With her father's health declining, Jillian picks up her life and returns to Crystal, Maine. At first, it seems time has stood still in her hometown. It doesn't take long for Jillian to realize nothing is quite the way she remembers.

Dr. Lily Davenport is the poster child for burnout—physically and emotionally. All she wants is a few months of nondemanding work at a summer camp, of all places, so she can figure out what to do with the rest of her life. The last thing she expects is to run into a woman who awakens a passion she hadn’t even realized had died along with all those she’d failed to save.

Zoey Cohen spent a lifetime learning to hide disappointment and loss behind a mask of unshakeable calm and control, even when her longtime friend-with-benefits lover moves on for true love. Declan Black returns to Philadelphia Medical Center after an accident costs her the life she’d built and her career. Zoey will never accept second place in matters of the heart, even when her rival is a career, and Dec has nothing left to give. Sometimes change is a force more powerful than will.

Flying-phobic ER nurse Olive Murphy is still gripping the armrest from her first-ever take-off when the pilot announces an in-flight medical emergency. Olive leaps into action and saves a life, but ends up getting stuck in the airport hours away from the marathon she's running in honor of her brother. Luckily for her, Stella Soriano, the stunning type A copilot, offers to give her a ride. After the two spend a magical day together, Stella makes a surprising request: Will Olive be her fake girlfriend?

There'd been a Rivers at the helm of Argyle Community Hospital for six generations, and Harper Rivers was set to take her father's place whenever he decided to hang up his shingle. Unfortunately, the board of directors had other ideas - they accepted a buyout offer from a health-care conglomerate with plans to close the hospital's doors to the community that depended on it. And Presley Worth, a high-powered corporate financier, came to town to oversee the closure.

Music runs through Annie Foster’s veins. A jingle writer by day and hostess of Coffee & Chords, an open-mic night at her best friend’s coffee shack, by night, Annie is doing exactly what she loves. Hitting the big time was never her dream. She has enough followers online to know her music matters. If it’s the right combination of success and happiness, why does she feel empty inside?

What do you do when your carefully planned life takes a wrong turn into hell? When Quinn Maguire, a dashing young trauma surgeon, unaccountably accepts a position as an ER physician, her new boss, Honor Blake, suspects that Quinn is hiding a dark secret. While the two declare an uneasy truce in an effort to work together, both struggle with mutual, and unexpected, attraction.

Unemployed university professor Tyler Marsh is pounding the pavement looking for a job. After a year of rejections based on her over-qualification, she's dumbed down her resume in a desperate attempt to get her foot in the door somewhere—anywhere. Chief Innovation Officer and wounded veteran Georgie DiNamico doesn't want an assistant or anyone else bothering her. But when Tyler's resume lands on her desk, along with a company background check listing the advanced degrees she omitted, Georgie sees an opportunity to add a researcher to her R&D team. 

Hannah Martin has an unusual job: she's a professional cuddler. While she has a big heart for her clients, she hasn't found someone special to snuggle up to in her personal life. Winter Sullivan isn't looking for love. She's an aloof workaholic who's built walls of ice around herself. She would rather drive toothpicks under her fingernails than cuddle, and she certainly doesn't want to share her space with anyone. When Winter's estranged father dies, he leaves her one last surprise: she and Hannah, a perfect stranger, will inherit a building together.