In a village in Wiltshire, just off a busy road, Larch Tree Lane winds slowly up a low hill. Among the residents is Maggie Hatherall, full of life despite her advancing years, who worries what she is going to do with her 200-year-old home. Lucia Grey has escaped a bad marriage but her ex is reluctant to let her start a new life free of him. And for architect Corin Drayton, an unexpected inheritance is the start of a complicated family wrangle. From the cottages and farms to the local shop, pub and old manor house, the residents' lives are set to intertwine and relationships bloom.

The three sisters of Victory Walk in East London will face heartache and tears on the home front. As rationing, blackouts and bombs start to bite, life will change forever for the three sisters.

When Emily Mattison falls victim to a near-fatal accident shortly after receiving an unexpected inheritance from a distant cousin, her ruthless nephew George seizes the opportunity to take control of his aunt's assets. It's only when Emily reaches The Drover's Hope, the former pub on the edge of the Lancashire moors bequeathed to her by her late cousin Penelope, that she begins to feel safe. She also discovers that love can be found in the most unexpected places. But it's not so easy to escape the clutches of someone as determined as George.

On her deathbed, Lucy Fallow's mother makes her twelve-year-old daughter promise to look after her four younger siblings and keep house for her father and two older brothers. When the Fallow menfolk lose their jobs they take work wherever they can. But it's not long before they are working on the wrong side of the law and under the watchful eye of Tom McKenzie. Meanwhile, through the hardship Lucy begins to form a relationship with Jacob McKenzie, the boy next door, and one evening they dance cheek to cheek in the moonlight and know that one day they will marry.

Cliffehaven, 1946. The war is over and those who have spent years fighting behind enemy lines are finally coming home. Peggy Reilly is over the moon that her husband Jim is safely back from Burma. But after the horrors he has endured, adjusting to life at Beach View will not be easy. Can he and Peggy find a way through? Meanwhile evacuee Ruby Clark has much to contend with when her estranged mother turns up, having completed a long prison sentence. There is huge heartache still to come for Ruby, and she will need her Beach View family more than ever.

Molly Peel feels trapped by her family: her ex-husband Craig cannot seem to abandon his controlling ways despite abandoning her for a younger woman, her lazy son Brian has long been taking advantage of her generosity, and her selfish daughter Rachel is embarrassed by her. When she is blamed for ruining Rachel’s wedding in circumstances beyond her control, Molly decides enough is enough and makes a clean break to Wiltshire to begin a new life. However, the persistent interference of her ex presents difficulties. Can Molly find the courage to stand up for herself and finally move on?

Pearl has given up on her dreams of being a journalist after being denied a promotion because of her gender. Joining the WAAF as a radio telephone operator for Bomber Command, Pearl's new job at RAF Fenthorpe serves two purposes – providing an income for her grandmother, and keeping a close eye on her younger sister, Thea, an instrument repairer at another Lincolnshire bomber station.

It's 1957, and three young women are beginning their nursing training at the Florence Nightingale Hospital in London's East End. Winne desperately wants to win her mother's approval - but will following in her footsteps and becoming a nurse help? Tearaway Viv has never been one to follow the rules, though the Nightingale may help her mend her ways. Beth is following her late sister's dream by training as a nurse. Will it be the right path for her? There's a steep learning curve ahead. But with friendship on their side, the Nightingale Daughters are ready to rise to the challenge.

London, 1944. With bombs raining over London, keeping the Battersea Tavern open is no easy feat for owner Winnie Berry - but the community need the warmth and familiarity of the pub more than ever. After marriage, Maureen Fanning had moved out to Wandsworth with her bad-tempered husband Brancher. But when he loses both his job and their lodgings, the only people who will take them in are her kindly grandparents, Len and Renee. Getting a cleaning job at the Battersea Tavern is the least she can do to pay them back. It would all be fine...if it weren't for Brancher.

Bristol 1936. Jenny Crawford has resigned herself to a loveless marriage living hand to mouth with their two children. Like many others, husband Roy struggles to find work at the docks but a chance encounter turns the family's fortunes around. Not only does he get regular work but they are also allocated a council house on Coronation Close on the outskirts of the city. Jenny and the children are overjoyed, this is the fresh start she could only ever dream of. But trouble feels never too far away.

Jane’s parents think Eddie’s rebellious ways will lead their beloved daughter into trouble. They forbid her from seeing Eddie, telling Jane to get a proper job as a nurse. But Jane cannot stand the idea of life without the boy she loves and secretly continues to see Eddie. The day she finds out that Eddie has betrayed her, she is utterly distraught. Were her parents right all along?

1850. When Opal Sharp finds herself and her younger siblings suddenly orphaned and destitute, she thinks things can get no worse. But soon three of them - including Opal - are struck down with the illness that took their father from them, and her brother Charlie is forced to make an impossible decision. Unable to afford a doctor, he knows the younger children will not survive. So, unbeknownst to Opal, Charlie takes their younger siblings to the workhouse, where he knows they will at least be fed and have a roof over their heads. Opal is heartbroken and struggles to forgive him. 

1864: Suddenly left as the head of the family, Kitty McKenzie must find her inner strength to keep her family together against the odds. Evicted from their resplendent home in the fashionable part of York after her parents' deaths, Kitty must fight the legacy of bankruptcy and homelessness to secure a home for her and her siblings. Through sheer willpower and determination, she grabs opportunities with both hands, from working on a clothes and rag stall in the market to creating a tea shop for the wealthy. 

When sixteen-year-old Sally is evacuated to the English south coast, she is terrified by what lies ahead of her. All she knows are the sights and sounds of London's East End – but Sally swallows her tears as they leave the familiar landmarks behind, knowing that she has to be a Grown-Up Girl and play mother to her six-year-old brother Ernie. Playing mother is nothing new for Sally – their real mother Florrie, a good-time girl, hasn't even come to the station to wave them off and Ernie, crippled at an early age by polio, is used to depending on his older sister.

October 1940. When VAD nurse Evie narrowly escapes being killed in an air raid during the London Blitz, it propels her to make a life-changing decision to break free of her troubled and unhappy life. She escapes to the Norfolk countryside to start afresh, with a job at the newly opened Great Plumstead Hall hospital, and a wonderful new home at Rookery House. The community of Great Plumstead welcomes evacuees to the village—mothers and children bombed out of their London homes. Sisters Prue and Thea, along with members of The Mother's Day Club, help the new arrivals settle in.