The Stoddard girls know no life but an itinerant one, trailing their father from town to town as he searches for work. And in every small town, their mother, Elizabeth, does her level best to make each sparse, temporary house they inhabit a home. But the fall of 1937 ushers in a year of devastating drought and dust storms, and the family's fortunes sink further when a questionable "accident" leaves Elizabeth and her girls alone to confront the cruelest hardships of these hardest of times.

The Colley family is made of modest farmers in the Missouri Ozarks. Although Southerners, the Colleys try to remain neutral, a fact ignored by the Union militia who confiscate their livestock, burn their farm, and arrest their daughter, Adair, on charges of “enemy collaboration”. Yet as this innocent young woman soon discovers, fate can have a double edge. While imprisoned, she falls in love with her interrogator, a Union major who helps her escape.

In March 1865, the long and bitter War between the States is winding down. Till now, 23-year-old Simon Boudlin has evaded military duty thanks to his slight stature, youthful appearance, and utter lack of compunction about bending the truth. But following a barroom brawl in Victoria, Texas, Simon finds himself conscripted, however belatedly, into the Confederate Army. Luckily his talent with a fiddle gets him a comparatively easy position in a regimental band.

It is 1870 and Captain Jefferson Kyle Kidd travels through northern Texas, giving live readings to paying audiences hungry for news of the world. An elderly widower who has lived through three wars and fought in two of them, the captain enjoys his rootless, solitary existence. In Wichita Falls, he is offered a $50 gold piece to deliver a young orphan to her relatives in San Antonio. Four years earlier, a band of Kiowa raiders killed Johanna's parents and sister; sparing the little girl, they raised her as one of their own.

Officer Ren Hopper is an enforcement ranger with the National Park Service, tasked with duties both mundane and thrilling: Breaking up fights at campgrounds, saving clueless tourists from moose attacks, and attempting to broker an uneasy peace between the wealthy vacationers who tromp through the park with cameras, and the residents of hardscrabble Cooke City who want to carve out a meaningful living. When Ren, hiking through the backcountry on his day off, encounters a tall man with a dog and a gun chasing a small black bear up a hill, his hackles are raised.