London 1950. Peggy Ronoscki is happily settling into life running her guesthouse on Mulberry Lane, surrounded by close friends and family. Life just seems too good...but then disaster strikes. Pip, her beloved son, is left in a coma following a devastating car crash, and a young girl collapses in the market, leaving Peggy no option but to nurse her back to health. As things begin to go awry, Peggy worries she has brought trouble to her doorstep Can her life ever return to normal? Or has Peggy’s good nature led her astray?

The hedonism of London in the Roaring Twenties is a world away from Annabel Tarleton's ordinary country existence. Until a chance meeting with the charming Richard Hansen at a society ball changes her life for ever. Annabel finds herself trapped inside a marriage that behind closed doors is cruel. Annabel has no choice but to flee and will do everything to save herself and her unborn baby. But the very powerful expect to get what they want.... 

It is two years since Harpers opened in Oxford Street and Ben is planning to expand the premises. Life is good for Sally and Ben as they look forward to their first child and hope for a prosperous future. Beth is settling into married life with Jack, gradually recovering from her aunt’s tragic death, though still unable to conceive a child. New girls have joined Harpers and Marion, Janice and Becky all become a part of the daily life at the busy store. Rachel is undecided whether to marry a man she isn’t sure she can trust, while Minnie meets an old love.

1949. Peggy and Able Ronoscki's seaside cafe in Devon is thriving, and their twins, Fay and Freddie, are growing up fast. To pursue her daughter’s destiny, Fay must train in London and Peggy is faced with a dilemma of moving the family back to London once more. Meanwhile, Peggy’s elder daughter, Janet, has her own troubles. She fears her husband is having an affair and is desperately unhappy. Peggy is torn two ways and can only hope that a reunion with her friends at Christmas can help resolve her problems. 

Liverpool, 1943. For Bella Rogers, life is looking up. She loves performing with The Bryant Sisters, the trio of singers who have become the country’s sweethearts, putting a smile on the faces of the brave boys fighting the Nazis. But then tragedy strikes when a telegram arrives: Bella’s beloved father has been killed in France. 

The women of Mulberry Lane anxiously wait for news. Peggy doesn’t know if she’ll ever again see Able, the American father of her twins, while a very odd letter from estranged husband, Laurie, threatens to set the cat among the pigeons. Rose can’t stop loving Jimmy, while Tom can’t stop loving her. Will Gordon ever again be the man he once was? Can he be a proper husband to Maureen, and if he can’t, what will become of their marriage?

The shop girls of Harpers Emporium on Oxford Street are happy in their work, and their lives are moving on at quite a pace. United by the suffragette cause and now living under one roof, some will find love and marriage whilst others experience heartache and tears. Harpers is the bond that holds them together, bringing strength through hardship and pain and friendship and love.

It is 1939, and working-class Evie Bishop has received a scholarship to study mathematics at Oxford when tragedy turns her life upside down. Evie must seek a new future for herself and, inspired to contribute to the war effort, joins the Women’s Auxiliary Air Force as an Ops Room plotter. Posted to a fighter station on the Sussex Coast, Evie befriends two other WAAFs. But the German bombers seem to know more than they should about the base’s operations, and soon Evie, May and Jess are caught up in a world more dangerous than they ever imagined. 

When Sally, Beth, Margaret and Rachel meet at a job interview for the wonderful new store in Oxford Street, they have no idea they will become lifelong friends. When all four girls are lucky enough to be selected as sales staff their exciting new adventure begins. Join them as they overcome heartbreak and grief, find love and happiness and remain united in their friendship, whatever life throws at them.

As the only female cabinet maker in the valley in 1935, Frankie Redfern is unusual. She faces prejudice even from her own mother. But she's content working for her father and is unwilling to give up her independence or the work she loves for marriage. When her husband falls gravely ill, Frankie's mother takes over, causing serious trouble for her daughter. And her cousin, an unscrupulous local builder, starts to help her for his own reasons.

Bristol, 1939. School leaver Maisie Miles suspects her father, a small-time crook, has an ulterior motive for insisting she gets a job at the W. D. & H. O. Wills tobacco factory but keeps it to herself. She's befriended by effervescent Phyllis Mason and kind-hearted Bridget Milligan who take pity on her and take Maisie under their wing. But beneath their happy-go-lucky exteriors, they all harbour dreams and worries about what the future holds. 

December 1930. With the Depression biting deeper, it looks like many children in the East End will wake up to nothing on Christmas morning. Widower Robbie Graham earns just enough to put food on the table for his children, Ben and Ruthie. Local cake shop owner Flo Hawkins can't bear the thought of any child having nothing for Christmas. Along with her sister, Honour, she hatches a plan to bring some festive cheer to the community.

Lizzie adores her beautiful and clever daughters and will do anything for them. Betty, the elder, is headstrong like Lizzie's first husband whilst Francie is talented and easily influenced. When Betty runs away after an argument with Sebastian, heartbreak and worry descend on the family. Sebastian is plunged into a dangerous overseas mission using his old contacts to track Betty to Paris and to the lair of the rogue who seduced her.

After the heartbreak of World War Two, newlywed midwife Cathy hoped Liverpool life would offer some joy. But a terrible miscarriage and the escape of her abusive stepfather Jack from prison make happiness hard to find. Meanwhile, Cathy’s beloved granny is ailing. Whilst at the hospital, Cathy sees her midwifery friends, who are planning to open a home for unmarried mothers. After losing a baby of her own, Cathy would love to help, but for now, she must take care of her grandmother.  

It’s 1943, and the district nurses have two new recruits. As the country ramps up for D-Day, the new nurses are getting to know their patients on their patch in London’s East End. Lily is quite sure of herself and doesn’t believe she has anything new to learn. She’ll find out the hard way that anyone can be made a fool of when she meets a man who promises her everything.