Pursuing his calling with singleness of vision, John Wesley defied the strength of angry mobs and longstanding traditions to offer the hope of Christ to millions of people who were outside the influence of the churches of the day. Passionate and tireless, this Anglican clergyman rode a quarter of a million miles on horseback during his lifetime, stopping to preach more than forty thousand sermons in open fields, churches, and barns.

As a fourteen-year-old intent on living a “modern” life, the last thing Isobel Kuhn wanted to grow up to be was a missionary. But as it turned out, this young agnostic’s life was redirected―from crisis and doubt to hope and strength. Convinced that God wanted her to preach the gospel as a China Inland missionary, Isobel bravely served among the Lisu people in remote mountainous regions of China and Thailand. After twenty years of ministry Isobel returned to the United States, writing stirring stories of faith and inspiring generations of people

John Newton's life was in a downward spiral. Impressed into the Royal Navy, John clashed with his fellow seamen and even became a servant alongside slaves in West Africa. When he found himself on a sinking ship, he called out to God for help. John began his conversion to Christianity while he captained a slave ship. Eventually he gave up his former life completely and became a minister with a deep passion for the gospel. A living witness to God's ability to change hearts, John joined the movement to set slaves free.

When Charles Mulli was a child, his family repeatedly abandoned him, and he lived in fear of his abusive, alcoholic father. With an extraordinary will, the young Kenyan struggled to feed and educate himself and, encountering hope in the gospel, found a reason to live and to forgive. Later, as a multimillionaire and father of eight, the entrepreneur sold his businesses to devote himself to caring for street children throughout Kenya. Since 1989, Charles and his wife, Esther, have taken into their protection thousands of the most vulnerable through Mully Children's Family.

One of the famous Doolittle Raiders who first attacked Japan after the bombing of Pearl Harbor, Jacob DeShazer knew his one-way mission was dangerous. Indeed, it led to his capture as a prisoner of war. Beaten, malnourished, and alone in his cell, Jacob was given a Bible—and far away from home, this American soldier became a Christian. After the war, Jacob returned to Japan and served his former enemy for thirty years as a missionary. His testimony of forgiveness and reconciliation—of love over hate—inspires a powerful gospel message for our lives today.

Six-year-old Ludwig was sitting at the table, reading his Bible and praying, when Swedish soldiers stormed through the castle door. Ludwig looked up at the soldiers and then returned to his prayer and reading. The soldiers stopped and stared--then left. They said they could not ransack a place that God watched over.

Betty Greene coaxed her Grumman seaplane to two thousand feet..... Suddenly, silence—total silence. The plane engine had stopped! Her passengers gasped, but Betty knew she must remain calm. They had only a slim chance for survival: the twisting jungle river below them.

As a poor Canadian farm boy, Jonathan Goforth had no idea that he would spend most of his life braving disaster, danger, and disease to share God's love with the people of China. But when God led him to do just that, nothing, not even the violent Boxer Rebellion, would stop Jonathan and his family from answering God's call. Making their home in China, the Goforths opened their doors to as many as five thousand visitors a month, all of whom heard the gospel message.

When he became God's smuggler, Brother Andrew was already familiar with risk. As a boy, the intrepid Andrew Van Der Bijl joined the Dutch Resistance against the Nazi occupation. As a young man, he fought eagerly in the Dutch East Indies—until the horror of war turned the adventure seeker to a life of alcohol and desperation. Redeemed by God, the Dutchman became a daring messenger of hope, smuggling Scripture through closed borders and equipping persecuted Christians behind the Iron Curtain.

Ten-year-old Lottie Moon had seen too much bitterness and gossip among churchgoers to want anything to do with religion or God. In fact, if there was a single way to waste a life, Lottie told herself, being a missionary was it. In a twist that only God could orchestrate, this spirited young girl who grew up to become the most educated woman in the American South would ultimately find her calling as a missionary to China.

George Muller stared at the beggar girl. She was no older than five and was piggybacking her little brother. Her mother had died in the cholera epidemic sweeping England. Her father had never returned from the mines. Standing in the muddy street, this little girl gave a face to Bristol's countless orphans. With scarcely enough food or money for his own family, George Muller opened his heart and home. Sustained by God's provision, the Muller house "Breakfast Club" of thirty orphans grew to five large houses that ultimately over ten thousand children would call home.

Growing up on the French-German border, son of a Lutheran pastor, Albert Schweitzer adopted a peace-loving approach to life. He studied theology, music, and philosophy and wrote numerous books. At age thirty he felt called to study medicine and eventually became a doctor. Together with his wife, Hélène, he founded a missionary hospital in Lambaréné, Gabon. Devoted to medical work in Africa, Albert was also a beacon of hope for a better future in war-ravaged Europe and was awarded the Nobel Peace Prize.

Jim and Pete turned to see the Auca men, their deadly spears raised, running toward Nate, Ed, and Roger. Jim stood in the river, his hand on his pistol. Should he defend himself? He already knew the answer. Each man had promised the others that he would not save himself by killing those they had sought out in Jesus' name. Jim Elliot and his coworkers surrendered their lives in Ecuador's jungle, trusting that their sacrifice would not be in vain. Decades later, this event has challenged countless Christians to live with one great purpose: to bring the gospel to those who have never heard.

In one decisive moment, Cameron Townsend understood that God had called him to translate the Bible into the language of his Guatemalan friends. For Cam, the obstacles were small when compared to the growing reward of helping the diverse people of Guatemala, Mexico, and Peru read God's life-changing Word for themselves. Quick on his feet and slow to give up, Cam started Wycliffe Bible Translators with the dream of making the Good News available in every language. Since 1942, Wycliffe has translated Scripture into hundreds of languages, spreading God's Word to people all over the world.

Amy Carmichael stood on the deck of the steamer, waving good-bye once again to her old friend Robert Wilson. How could she have known she would never see him or the British Isles again? Amy was certain God had called her to India. Indeed! India would be home for the rest of her life. Amy's life was marked by a simple, determined obedience to God, regardless of circumstances. Her story and legacy are stunning reminders of the impact of one person who will fear God and nothing else.