When Claire, an overachieving psychologist with OCD tendencies, hires Lana, an impulsive, out-of-work actress for a fake relationship, she figures the worst she'll have to endure are the messes Lana leaves around. It's only for a few months anyway. And it's not as if she'll enjoy all those fake kisses and loving looks. Right?  

Dr. Hope Finlay loves her job as an emergency room physician, especially since it allows her only brief encounters with her patients. She learned early in life not to get attached to anyone because it never lasts. Laleh Samadi, a waitress at her aunt’s restaurant, is the exact opposite. She easily connects with people and loves her big, boisterous Persian family, despite their tendency to meddle in her life. When Laleh needs to be rushed to the ER with heart trouble, Hope saves her life. Afterwards, strange things begin to occur.

Dr. Jordan Williams devotes her life to two things: saving patients in the operating room and pleasuring her latest conquest in the bedroom. Her idea of commitment is spending a few hours together in bed. Single mom Emma Larson is Jordan’s polar opposite. Family and fidelity mean everything to her. After an ugly divorce from her wife, a plastic surgeon, she and her five-year-old daughter move in next door to Jordan. While she finds Jordan undeniably attractive, falling in love with another womanizing surgeon is the last things she needs.

Hannah Martin has an unusual job: she's a professional cuddler. While she has a big heart for her clients, she hasn't found someone special to snuggle up to in her personal life. Winter Sullivan isn't looking for love. She's an aloof workaholic who's built walls of ice around herself. She would rather drive toothpicks under her fingernails than cuddle, and she certainly doesn't want to share her space with anyone. When Winter's estranged father dies, he leaves her one last surprise: she and Hannah, a perfect stranger, will inherit a building together.

Flirting has never been Denny’s strong suit, but so what if she’s too shy to ask women out? She’s content with her simple life, working as a cashier and helping her sister raise her niece. But then she gets a wrong-number text message from a stranger named Eliza, asking her of all people for dating advice!