After 25 years of traveling and shaping the American West with her husband, Robert Strahorn, a railroad promoter, investor, and writer, Carrie Strahorn decides to write down what was really on her mind during those adventurous nomadic years. Certain that her husband will not read it, and in fact that it will only be found after her death, Carrie is finally willing to explore the lessons she learned along the way, including the danger a woman faces of losing herself within a relationship with a strong-willed man and the courage it takes to accept her own God-given worth apart from him.

In 1844, two years before the Donner Party, the Stevens-Murphy company left Missouri to be the first wagons into California through the Sierra Nevada Mountains. Mostly Irish Catholics, the party sought religious freedom and education in the mission-dominated land and enjoyed a safe journey - until October, when a heavy snowstorm forced difficult decisions. The first of many for young Mary Sullivan, newlywed Sarah Montgomery, the widow Ellen Murphy, and her pregnant sister-in-law Maolisa. 

Already well-versed in the natural healing properties of herbs and oils, Jennie Pickett longs to become a doctor. But the Oregon frontier of the 1870s doesn't approve of such innovations as women attending medical school. To leave grief and guilt behind, as well as support herself and her challenging young son, Jennie cares for an elderly woman using skills she's developed on her own. When her patient dies, Jennie discovers that her heart has become entangled with the woman's widowed husband, a man many years her senior.

Eliza Spalding Warren was just a child when she was taken hostage by the Cayuse Indians during a massacre in 1847. Now the young mother of two children, Eliza faces a different kind of dislocation; her impulsive husband wants them to make a new start in another territory, which will mean leaving her beloved home and her departed mother's grave - and returning to the land of her captivity.

In 1853, Abigail Scott was a 19-year-old school teacher in Oregon Territory when she married Ben Duniway. Marriage meant giving up on teaching, but Abigail always believed she was meant to be more than a good wife and mother. When financial mistakes and an injury force Ben to stop working, Abigail becomes the primary breadwinner for her growing family. What she sees as a working woman appalls her, and she devotes her life to fighting for the rights of women, including their right to vote.

Returning to her Midwest roots, award-winning author Jane Kirkpatrick draws a page from her grandmother's photo album to capture the interplay between shadow and light, temptation and faith that marks a woman's pursuit of her dreams.

Three generations of the Brown women travel west together on the Oregon Trail, but each seeks something different. When the trail divides, a decision must be made that could bring survival or tragedy. The challenges faced will form the character of one woman - and impact the future for many more.

Faith Allen went to live with her aunt and uncle in the Kentucky mountains after her parents died. They hadn’t been cruel, but they hadn’t been loving and kind, either; and they expected her to work hard. When their son strikes it rich in the California gold rush, they pack up to head to California via the Oregon Trail.

Worie Dressar is 17 years old when influenza and typhoid ravage her Appalachian Mountain community in 1877, leaving behind a growing number of orphaned children with no way to care for themselves. Worie’s mother has been secretly feeding several of these little ones on Sourwood Mountain. But when tragedy strikes, Worie is left to figure out why and how she was caring for them. 

Ingrid Chastain readily agreed to accompany her father to deliver vaccines to a mining town in the Montana Territory. She never could have anticipated a terrible accident would leave her alone and badly injured in the wilderness. When rescue comes in the form of a mysterious mountain man who tends her injuries, she's hesitant to put her trust in this quiet man who seems to have his own wounds. 

Unflinching and plainspoken, Tessa Swan is not your typical 18th-century woman. Born and bred on the Western Virginia frontier along with her five brothers, she is a force to be reckoned with. Quiet and courageous, Clay Tygart is not your typical 18th-century man. Raised by Lenape Indians, he returns a hero from the French and Indian War to the fort that bears his name, bringing with him Tessa's long-lost friend, Keturah, a redeemed Indian captive like himself. Determined to avoid any romantic entanglements as fort commander, Clay remains aloof whenever he encounters the lovely Tessa.

After years of schooling on the East Coast, Constance Browning returns to Oregon and the reservation where she grew up with her missionary parents. She is accompanied by Thomas Lowell, her best friend and colleague, and together they embark on a project to catalogue the native peoples of Oregon for the Bureau of American Ethnology. But Connie and Tom have another purpose - to prove her parents are not involved in a secret conspiracy to goad the oppressed tribes into a doomed war.   

Joel Vargas can't believe he's lost his older brother in the wilds of the Rocky Mountains after surviving their harrowing voyage across the Atlantic. And he can't shake the feeling that Adam - his only living relative - is in dire trouble. No matter what the cost, he and his band of friends won't stop until Adam is found. He's not sure if two Indian women they meet on the way will be a help or hindrance.

Susanna Wilkins will do anything to make her father's final dream come true, including trek along the path Lewis and Clark explored into the untamed wilds of the Rocky Mountains. Every mile is more crucial now that lung cancer is stealing Pa's last days faster than she can come to terms with losing him. The journey becomes harder than she ever expected, but paddling upriver through fierce rapids and fighting hungry grizzlies isn't what terrifies her the most.

Determined to prove her worth, Meksem fiercely fought to earn her place among the warriors in her Nez Perce camp. When her half-sister is captured by an enemy tribe, she refuses to trust the rescue to anyone else. But her new friends insist on joining her mission, and she battles between relief and frustration at their presence. Especially the white man who peers at her as if he can see through the face of the warrior she struggles so hard to maintain.