After 25 years in prison for a senseless juvenile murder, Gordon Loomis returns to a changed world. His old neighborhood is blighted by drug dealers and neglected property. His brother, Dennis, a successful oral surgeon, tries to help but is torn by his own fears and failings. Gordon's persistent visitor, the flamboyant Delores Dufault yearns to be part of his new life, but he is as afraid of relationships as he is of being sent back to jail.

Ava only left her daughter in the pushchair for five minutes. The buckle was fastened, and she was sure it was safe. But when she came downstairs, the door was open and Abi was gone - she walked down the road, past the Lovegoods' house, and was never seen again. A year later, the Lovegoods throw a housewarming party, showing off the results of their renovation. Ava doesn’t want to go. She can’t bear to look down that end of the road, to see the place where Abi vanished, and she doesn’t want to spend time with people who don’t share her grief. 

Since the turn of the century, a generation has come of age knowing only war, recession, political gridlock, racial hostility, and a simmering fear of environmental calamity. In the country’s forgotten pockets, where industry long ago fled, where foreclosures, Walmarts, and opiates riddle the land, death rates for rural whites have skyrocketed, fueled by suicide, addiction, and a rampant sense of marginalization and disillusionment. This is the world the characters in Stephen Markley’s brilliant debut novel, Ohio, inherit. This is New Canaan.

Tom Lowe’s identity and his pride are invested in the work he does with his back and his hands. He designed and built his family’s dream home, working extra hours to pay off the adjustable rate mortgage he took on the property, convinced he is making every sacrifice for the happiness of his wife and son. Until, in a moment of fatigued inattention, shingling a roof in too-bright sunlight, he falls. In constant pain, addicted to painkillers at the cost of his relationships with his wife and son, Tom slowly comes to realize that he can never work again.

When they meet in the 1930s, Doris and Tup’s love is immediate. They marry quickly and Doris commits to the only life Tup ever wanted: working the Senter family farm. Soon their first child, Sonny, is born and Doris and Tup understand they are blessed. More children arrive - precocious, large-hearted Dodie and quiet, devoted Beston - but Doris and Tup take nothing for granted. When an unimaginable tragedy turns the family of five into a family of four, everything the Senters held faith in is shattered.