Matthew Bartholomew, unorthodox but effective physician to Michaelhouse college in medieval Cambridge, is as worried as anyone about the pestilence that is ravaging Europe and seems to be approaching England. But he is distracted by the sudden and inexplicable death of the Master of Michaelhouse - a death the University authorities do not want investigated.

As the leading churchmen and women gather at the Synod of Whitby in AD 664 to debate the rival merits of the Celtic and Roman Churches, tempers begin to fray. Conspirators plot an assassination, while mysterious, violent death stalks the shadowy cloisters of the Abbey of St Hilda. When the Abbess Etain, a leading speaker for the Celtic Church, is found murdered, suspicion inevitably rests on the Roman faction. Attending the Synod is Fidelma, of the community of St Brigid of Kildare.

Lady Emily Hardcastle is an eccentric widow with a secret past. Florence Armstrong, her maid and confidante, is an expert in martial arts. The year is 1908 and they've just moved from London to the country, hoping for a quiet life. But it is not long before Lady Hardcastle is forced out of her self-imposed retirement. There's a dead body in the woods, and the police are on the wrong scent. Lady Hardcastle makes some enquiries of her own, and it seems she knows a surprising amount about crime investigation...

In 1360 Edward III issues a call to arms, as sporadic attacks by the French threaten to turn into a full-blown invasion. In Cambridge, fear of the enemy is magnified by the belief that foreign agents are lurking in the area. Tension runs ever higher as rumours and ignorance fan the flames of suspicion amid preparations for war. And then the first murder occurs - of a French scholar living in the town.

England, 1176. Aelred Barling, esteemed clerk to the justices of King Henry II, is dispatched from the royal court with his young assistant, Hugo Stanton, to investigate a brutal murder in a village outside York. The case appears straightforward. A suspect is under lock and key in the local prison, and the angry villagers are demanding swift justice. But when more bodies are discovered, certainty turns to doubt - and amid the chaos it becomes clear that nobody is above suspicion.

Detective Chief Inspector Ryan retreats to Holy Island seeking sanctuary when he is forced to take sabbatical leave from his duties as a homicide detective. A few days before Christmas, his peace is shattered, and he is thrust back into the murky world of murder when a young woman is found dead amongst the ancient ruins of the nearby priory. When former local girl Dr. Anna Taylor arrives back on the island as a police consultant, old memories swim to the surface, making her confront her difficult past.

One fine day, A.D. 70, Sosia Camillina quite literally runs into Marcus Didius Falco on the steps of the Forum. It seems Sosia is on the run from a couple of street toughs, and after a quick and dirty rescue, P.I. Falco wants to know why.

It is the spring of 1297, and young wife Margaret Kerr is desperately afraid.

The year is 937. England is a nation divided, ruled by minor kings and Viking lords. Each vies for land and power. The Wessex king Æthelstan, grandson of Alfred the Great, is readying himself to throw a spear into the north. Behind him stands Dunstan, the man who will control the destiny of the next seven kings of England and the fate of an entire nation. Welcome to the original game for the English throne.

Spring, 1663: public London is executing plans to mark the third anniversary of the Restoration. Private London, murky, dangerous and seething with intrigue, is entertaining other plans. And other executions - for the death of wealthy merchant Matthew Webb and the killing of an apparent vagrant during a royal procession. Thomas Chaloner, spy for the king's intelligence service, soon realises that two murders point in one direction: upwards, towards the great and supposedly good.