Captain Dominic Holland leads a crew of skilled covert operatives and talented scientific personnel. He's taken them to all corners of the Earth to protect the United States from biological and chemical warfare. When his CIA handler, Meredith Webb, gives him a mission to investigate a disturbing lead on a laboratory based out of an abandoned oil rig, they discover the most terrifying threat to mankind they've ever faced - a genetically engineered biological weapon called the Oni Agent.
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Governments across the globe have failed to stop the spread of the Oni Agent. The biological weapon continues to wreak havoc. Those that are infected become abominations known as Skulls, a fate worse than death. Captain Dominic Holland and Meredith Webb have made it to Fort Detrick. The Army base was once a bastion for America's biodefense. Now, swarms of hungry Skulls prowl outside the walls.
A man-made plague has ravaged humanity, the military is in shambles, and chaos reigns over the world. Hope seems nothing more than a dream. Captain Dominic Holland is determined to stop the inevitable. His daughters are finally safe, and his crew has found new ways to combat the Skulls. He leads the Hunters on a mission to recover vital research that may hold the key to stopping the biological agent responsible for this apocalyptic new world. Can the Hunters salvage what remains of humanity? Or is it already too late?
Captain Dominic Holland's greatest weapon against the apocalypse is his ship. The Huntress is the heart of Dom's scientific research and military operations. And it has been taken. Dom must embark on a perilous mission to retake it if he stands any chance at finding the cure the world so desperately needs. Dom's daughter, Kara, is stranded in the middle of Skull-infested Virginia. While she and a few others struggle to reunite with Dom and the Hunters, enemies more terrifying and ruthless than the Skulls emerge.