Starting a cannabis company is supposed to be chill, right? George, Brandy and Marcus are about to find out just how sobering the cannabis business can be.

When George has the idea to quit his job as a pharmacist and form a weed start-up with some equally inexperienced friends, he doesn’t realize just how difficult it will be to stake a claim in the market - especially when his personal life is in total and complete chaos.

Part stoner comedy, part L.A. satire, part cautionary tale about opening a business with your friends, Yes We Cannabis stars top-notch comedy talent including Sam Richardson (I Think You Should Leave, The Afterparty), Langston Kerman (South Side, Insecure) and Punkie Johnson (Saturday Night Live, Love Life) along with appearances from Richard Kind, Method Man, Tim Meadows, Rachel Dratch and more.

As their troubles mount and their friendship begins to feel the strain of their newfound business, the trio at the center of Yes We Cannabis must confront a dire question: Does Yes We Cannabis have what it takes to thrive, or will it land up in the ashtray of history?