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This isn’t medical advice — always talk to your doctor before making any health decisions

What happens after weight loss, when biology pushes back and maintenance becomes the hardest part?

In this episode of The Plus SideZ Podcast, we explore weight loss maintenance on GLP-1s through the lived experience of Ro patient and fitness instructor CeCe, who lost over 100 pounds through diet and exercise before turning to a GLP-1 to help sustain her progress. CeCe shares what it’s like navigating hunger, identity, and bias in the fitness industry while living in a changing body, and why weight maintenance often requires more than willpower alone.

Ro Chief Medical Officer Dr. Melynda Barnes joins the conversation to ground CeCe’s experience in science, explaining obesity as a chronic metabolic disease, how GLP-1 medications support long-term weight maintenance, and why movement and nutrition matter regardless of body size. Together, they unpack the impact of weight stigma in healthcare and fitness spaces, and what compassionate, evidence-based obesity care should actually look like.

This episode is for anyone questioning why keeping weight off is so difficult, feeling judged for their body while prioritizing health, or seeking a clearer, stigma-free understanding of GLP-1s and long-term care.

Community Guest:

CeCe’s - Socials https://www.instagram.com/ceceolisa/?hl=en

Professional Guest:

Chief Medical Officer Dr. Melynda Barnes

LinkedIn: https://www.linkedin.com/in/melyndabarnes/

Bio - https://ro.co/weight-loss/dr-melynda-barnes/

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