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Weight Loss After Breast Cancer: Deep Dive in to a Large Clinical Trial

Weight Loss After Breast Cancer: Deep Dive in to a Large Clinical Trial

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I break down a new large clinical trial that examined weight loss outcomes in women with stage II–III breast cancer after treatment. We explore what the year-long lifestyle intervention included, how much weight participants lost, and why average numbers don’t tell the full story. I discuss differences in weight loss by menopausal status and race, common frustrations survivors experience, and where GLP-1 medications may fit into weight management after breast cancer.


Ligibel JA, Ballman KV, McCall L, et al. Impact of a Weight Loss Intervention on 1-Year Weight Change in Women With Stage II/III Breast Cancer: Secondary Analysis of the Breast Cancer Weight Loss (BWEL) Trial. JAMA Oncol. 2025;11(10):1194-1203. doi:10.1001/jamaoncol.2025.2738

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