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Updates in HIV PEP Protocols and Guidelines

Updates in HIV PEP Protocols and Guidelines

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Recent updates to U.S. guidelines for HIV post‑exposure prophylaxis (PEP) provide modernized recommendations for both non‑occupational and occupational exposures — reflecting advances in antiretroviral therapy and evolving evidence. This course summarizes key changes, including preferred regimens, testing/follow‑up modifications, and special‑population considerations, and explores how these updates influence clinical practice. You will gain the practical knowledge needed to inform prompt PEP decision‑making, patient counseling, and care coordination.

HOST
Rachel Maynard, PharmD

GameChangers Podcast Host and Clinical Editor, CEimpact
Lead Editor, Pyrls

GUEST
Kenric Ware, Pharm D
Clinical Associate Professor of Pharmacy Practice
Mercer University


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CPE INFORMATION
Learning Objectives

Upon successful completion of this knowledge-based activity, participants should be able to:
1. Identify current guideline recommendations for initiating HIV PEP after occupational and non-occupational exposure.
2. Describe key considerations for selecting and managing HIV PEP regimens.

Rachel Maynard and Kenric Ware have no relevant financial relationships with ineligible companies to disclose.

0.05 CEU/0.5 Hr
UAN: 0107-0000-26-052-H01-P
Initial release date: 2/16/2026
Expiration date: 2/16/2027
Additional CPE details can be found here.

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