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This Week in Virology

This Week in Virology

By: Vincent Racaniello
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Summary
 TWiV is a podcast about viruses - the kind that make you sick.Vincent Racaniello 2022 Biological Sciences Nature & Ecology Science
Episodes
  • TWiV 1374: Clinical Update with Dr. Daniel Griffin

    TWiV 1374: Clinical Update with Dr. Daniel Griffin
    Nov 14 2026
    In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the identification of a type 1 poliovirus outbreak in Syria, the loss of US measles elimination status, use of the influenza vaccine against melanoma, death in Florida from dengue virus infection and return of the virus to the US, wider use of the Ebola ERVEBO vaccine, before Dr. Griffin deep dives into recent statistics on RSV, influenza, SARS-CoV-2 infections and measles, the FDA-approved package inserts for the RSV biologic products, and the magnitude and durability of the immune response following administration of the COVID-19 vaccine in children. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Syrian Arab Republic launches coordinated public health response following poliovirus detection in Deir Ezzor (WHO)The U.S. Has Lost Its Measles-Elimination Status, Data Suggests (NY Times)Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma (Clinical Trials.gov)501 Phase 1b trial of intratumoral administration of the seasonal influenza vaccine in patients with melanoma (BMJ Journals: Journal for ImmunoTherapy of Cancer)Why the simple flu shot could be a surprise weapon against cancer (Washington Post) Dengue (WHO: Dengue)Her Death From Dengue May Signal That the Disease Is Here to Stay (NY Times)Why H5N1 in mink is concerning (JPWeiland: X)Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service)CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newsroom)Ebola DRC (X)Ebola dashboard (ebola.fyi) EBOLA: The Democratic Republic of the Congo, 2026 (WHO)Wider use of Ervebo vaccine urged as DR Congo Ebola outbreak nears 11,000 cases (CIDRAP) Wastewater for measles (WastewaterSCAN)Impact of a large measles outbreak associated with transmission in the Americas and Canada's loss of measles elimination status: descriptive cohort study (the bmj)In America's measles epidemic, RFK Jr. is now on trial (Politico)Measles cases and outbreaks (CDC Rubeola) Measles Dashboard (South Carolina Department of Public Health)Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services)Measles (VDH: Virginia Department of Health)Tracking Measles Cases in the U.S. (Johns Hopkins) New Measles Dashboard (Hospital + HealthSystem Association of Pennsylvania) Measles (Commonwealth of Pennsylvania) Measles Dashboard (New York State: Department of Health)Weekly measles and rubella monitoring (Government of Canada)Measles (WHO)Get the FACTS about measles (NY State Department of Health)Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC)Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)Measles Vaccination: Know the Facts (IDSA: Infectious Diseases Society of America)Deaths following vaccination: what does the evidence show (Vaccine)Laboratory Testing for Measles (CDC: Measles (Rubeola))Measles Clinical Diagnosis Fact Sheet (CDC: Measles (Rubeola))Measles Serology Testing (CDC: Measles (Rubeola))New York State Seasonal Respiratory Virus Dashboard (New York State: Department of Health) Four Medical Societies, in Panel Led by UMSOM Expert, Back One Set of Flu, RSV and COVID-19 Vaccine Recommendations (University of Maryland: School of Medicine)Influenza: Waste water scan for 11 pathogens (WastewaterSCAN)US respiratory virus activity (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)Weekly surveillance report: cliff notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)RSV: Waste water scan for 11 pathogens (WastewaterSCAN) Respiratory Diseases (Yale School of Public Health)US respiratory virus activity (CDC Respiratory Illnesses)RSV-Network (CDC Respiratory Syncytial virus Infection)Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) BEYFORTUS (FDA: package insert) ENFLONSIA (FDA: package insert)AREXVY (FDA: package insert)ABRYSVO (FDA: package insert)MRESVIA (FDA: package insert)Effectiveness of the mRNA-1345 Vaccine Against Respiratory Syncytial Virus in US Veterans (JAMA Network Open)Waste water scan for 11 pathogens (WastewaterSCAN)COVID-19 deaths (CDC)Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)COVID-19 national and regional trends (CDC)COVID-19 variant tracker (CDC)SARS-CoV-2 genomes galore (Nextstrain) Moderna Receives U.S. FDA Approval for Updated 2026-2027 COVID-19 Vaccines (...
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    59 mins
  • TWiV Special: Measles Mini Symposium

    TWiV Special: Measles Mini Symposium
    Nov 12 2026

    Vincent travels to the 8th Measles Mini Symposium at the Mayo Clinic in Rochester, MN where he meets with Paul Rota and Patrick Sinn to discuss their careers and their work on measles virus.

    Host: Vincent Racaniello

    Guests: Paul Rota and Patrick Sinn

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of TWiV!

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.
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    54 mins
  • TWiV 1373: Challenging Dengue and RIGging Flu

    TWiV 1373: Challenging Dengue and RIGging Flu
    Nov 8 2026

    TWiV explains results of a dengue virus human challenge which reveals that preexisting immunity shapes viral replication and broadly protective responses, and how influenza virus antagonizes self-sensing by RIG-I to enhance viral replication.

    Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • Support science education at MicrobeTV
    • Democratic doctors win big in 2026 midterm elections (CIDRAP)
    • Florida's dengue total jumps to 485 (CIDRAP)
    • Dengue virus human challenge study (Sci Transl Med)
    • Influenza virus and self sensing of host by RIG-I (Cell Rep)
    • Letters read on TWiV 1373
    • Timestamps by Jolene Ramsey. Thanks!
    Picks of the Week

    Brianne – Five Science-Backed Benefits of 'grandma hobbies'
    Kathy – Bird of the Week from Ben Tonelli
    Alan – The Dark Frontier, by Jeffrey Marlow
    Vincent – Where Do Photons Actually Go When You Turn Off The Light?

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.
    Show More Show Less
    1 hr and 50 mins
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