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The Pound of Cure Weight Loss Podcast

The Pound of Cure Weight Loss Podcast

By: Matthew Weiner MD and Zoe Schroeder RD
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Summary

Hosted by obesity specialist Matthew Weiner, MD and dietitian Zoe Schroeder, RD, The Pound of Cure Weight Loss Podcast provides a comprehensive approach to weight loss. We cover nutrition, the new GLP-1 medications, and Bariatric Surgery in depth and answer tons of questions from our audience every week. Check out our website for video versions of the podcast: www.poundofcureweightloss.com/podcast

© 2026 The Pound of Cure Weight Loss Podcast
Hygiene & Healthy Living Physical Illness & Disease
Episodes
  • Episode 82: It's Not Willpower: Brain Science Proves Your Weight Struggle Is Neurological (And Fixable) with Dr. Steve Rondeau
    Apr 20 2026

    What if your struggle with weight loss isn't about willpower at all, but about brain patterns you were born with? In this groundbreaking conversation, Dr. Matthew Weiner and registered dietitian Zoe sit down with neuroscientist Dr. Steve Rondeau, who has conducted over 50,000 EEG brain scans and just released his book Think Like a Brain. Dr. Rondeau reveals that emotional eating, stress eating, and food cravings aren't character flaws—they're measurable brain patterns that show up differently in every person. His research has identified that what we call "stress eating" can manifest in 4,096 different combinations of brain patterns, explaining why the same diet works for one person but fails for another.

    One of the most exciting revelations is the potential to use brain scans to predict who will respond to GLP-1 medications like Ozempic, Wegovy, and Zepbound before they even take their first dose. Dr. Rondeau discusses the "overwhelmed pattern"—a specific brain biomarker where brain activity slows down under stress, strongly correlated with using food as an escape mechanism. He draws fascinating parallels between GLP-1 medications and psychedelic therapy, explaining how both create a window of opportunity where the usual noise quiets down enough for real behavioral change to happen. The key is using that window effectively with proper integration work.

    This episode challenges the entire foundation of mental health diagnosis, revealing why the DSM is fundamentally flawed and how brain scan technology can finally match treatments to individual biology rather than broad symptom categories. Dr. Rondeau uses the powerful analogy of a husky in the desert versus the mountains—your brain patterns may be perfectly adapted for certain situations but set you up for failure in others. The conversation explores emerging wearable EEG technology, the inheritance of brain patterns, and the future of truly personalized medicine. Essential listening for anyone who has ever wondered why willpower never seems to be enough.

    Connect with Dr. Steve Rondeau:

    • Book: Think Like a Brain (thinklikeabrain.com)
    • Available on Amazon, Barnes & Noble, and all major platforms
    • Audiobook coming soon

    Download the Pound of Cure App: gololi.ai - AI-powered personalized weight loss planning

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    1 hr and 7 mins
  • Episode 81: How Bariatric Surgery and Nutrition Changed Moira's Life
    Apr 6 2026

    In this inspiring episode, Moira shares her transformative journey through weight loss, bariatric surgery, and lifestyle changes. Discover practical strategies for sustainable health, the importance of exercise safety, and how combined treatments can empower lasting weight management.

    Sign up to beta test our new app! gololi.ai

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    32 mins
  • Episode 80: The Future of GLP-1 Medications: Quick Pen and Dose Flexibility
    Mar 29 2026

    In this episode, Dr. Weiner and Zoe discuss the latest advancements in obesity medicine, including the beta launch of their new app Loli, the evolution of GLP-1 medication dosing with the Quick Pen, and insights from recent research on GLP-1 prescribing practices. They also address patient questions on post-bariatric care and the future of medication delivery.

    Sign up to be a beta tester for our new app - https://gololi.ai

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    33 mins
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