David Remnick sits down with Mickey Down and Konrad Kay, the creators of a show he loves, “Industry,” which is currently airing its fourth season. The show is centered on the financial and personal dramas of junior employees at a fictional London investment bank. Down and Kay are old friends who both did unsuccessful stints in banking. “Before we could formulate our own identities, we allowed the institution to make them for us,” Down tells Remnick. But, having left finance for television, he says, “I still feel like I want to make money. . . . I’m never content with my career. The reason our show feels like it’s constantly changing and vibrating with electricity is because me and Konrad are, in terms of our careers. And, you know, we want to be successful. We were finance bros in the first instance.”

New episodes of The New Yorker Radio Hour drop every Tuesday and Friday. Join host David Remnick as he discusses the latest in politics, news, and current events in conversation with political leaders, newsmakers, innovators, New Yorker staff writers, authors, actors, and musicians.

As Donald Trump and his Administration threaten to attack Iran, their motivations remain unclear. Does the President want to force Iran to make a nuclear deal, to replace the one that he scrapped in his first term, or is he really seeking regime change? To understand how this all might play out, David Remnick speaks with Karim Sadjadpour, a policy analyst at the Carnegie Endowment for International Peace, who writes about the Middle East for Foreign Affairs and other publications. Citing the disastrous precedents in Afghanistan and Iraq, Sadjadpour notes, “the last two decades has proven that we don’t have the ability to dictate . . . who comes to power the day after a military attack.”

Plus, After protests over the economy erupted across Iran late last year, reports emerged that the regime was killing protesters. Donald Trump threatened to intervene, but did not. Estimates vary widely, but some note that thirty thousand people or more may have been killed. Now, as the U.S. sends a huge military force to the Gulf, Iranians are waiting for war—and many in the country are in the shocking position of hoping for conflict, if it will end the Ayatollah’s government. The reporter Cora Engelbrecht has been recording her conversations with sources on the ground about what that could mean. Their voices were altered or overdubbed for our story, to protect them from reprisal.

New episodes of The New Yorker Radio Hour drop every Tuesday and Friday. Join host David Remnick as he discusses the latest in politics, news, and current events in conversation with political leaders, newsmakers, innovators, New Yorker staff writers, authors, actors, and musicians.

Ozempic and other GLP-1 drugs have had a major impact in their short time on the market—currently, one in eight Americans say that they have been on GLP-1 drugs. As tens of millions of people take these medications, anecdotal evidence has emerged that they have a positive effect on alcohol abuse and drug addiction. Researchers are starting to run trials of the drugs for these purposes, and some speculate that GLP-1 drugs could even affect addiction behaviors such as gambling and online shopping. The physician and New Yorker medical correspondent Dhruv Khullar spoke with scientists and patients. “Over the course of my reporting,” he tells David Remnick, “I became more and more bullish on the idea that these are actually going to be really important molecules for the treatment of addiction.”

Dhruv Khullar’s “Can Ozempic Cure Addiction?” was published on February 9th.

New episodes of The New Yorker Radio Hour drop every Tuesday and Friday. Join host David Remnick as he discusses the latest in politics, news, and current events in conversation with political leaders, newsmakers, innovators, New Yorker staff writers, authors, actors, and musicians.