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The Metabolic Link

The Metabolic Link

By: Dr. Dominic D'Agostino PhD Dr. Angela Poff PhD and Victoria Field
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Welcome to The Metabolic Link, a medical and science podcast that explores the common thread of metabolism in health and disease. Join Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field as they dive into the latest research on metabolic health and therapy alongside some of the world’s leading experts. They'll also discuss how this science is being applied in the real world. This is where science meets society.© 2025 The Metabolic Link Hygiene & Healthy Living Physical Illness & Disease
Episodes
  • Metabolic Therapy for Pets: The Future of Veterinary Medicine | Dr. Loren Nations | The Metabolic Link Ep. 79
    Oct 21 2025

    When veterinarian Dr. Loren Nations lost his wife to aggressive cancer despite the best conventional treatments, he didn't just grieve—he revolutionized his entire approach to medicine. In this deeply personal conversation, Dr. Nations reveals how tragedy led him to discover that our pets are experiencing metabolic disease at rates even higher than humans, with 61% of cats and 59% of dogs now obese.

    Dr. Loren Nations is a board-certified veterinarian with over 30 years of experience. He's the founder of Veterinary Healthcare Associates, Ascend Vets, and Neoteric, pioneering the integration of ketogenic nutrition, hyperbaric oxygen therapy, and metabolic medicine into veterinary care.

    Questions Answered in This Episode:

    • What metabolic-based therapies are you using alongside standard care, and which have proven most effective?
    • Can dogs and cats safely eat ketogenic diets without developing pancreatitis?
    • How do you approach gut healing in pets, and what specific strategies or supplements do you use beyond nutrition?
    • What happens when you treat pet cancer with metabolic therapies instead of just conventional oncology?
    • What can veterinary medicine teach us about human metabolic health?

    This conversation bridges two worlds we rarely see connected—showing how the metabolic principles transforming human health apply equally to our animal companions, and how healing our pets might just teach us to heal ourselves.

    Join us on November 12th for a live Q&A with Dr. Nations on The Metabolic Initiative.

    Neoterric: Find Dr. Nations' online education for pet parents here.
    Veterinary Healthcare Associates: Learn about Dr. Nations' animal hospital here.
    KetoPet: Read scientific articles on the ketogenic diet for pets here.

    Special thanks to the sponsors of this episode:
    ✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here!
    ✅ iRestore - Get a huge discount on the iRestore Illumina Face Mask when you use the code METABOLICLINK here
    ✅Piquelife.com - Get the Pu'er Bundle for 20% off here.

    In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

    You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

    Find us on social:

    • Instagram
    • Facebook
    • YouTube
    • LinkedIn

    Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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    1 hr and 9 mins
  • Can a Ketogenic Diet Improve Sleep Apnea? | Dr. Jonathan Jun | The Metabolic Link Ep. 78.
    Oct 8 2025

    What if the food you eat could change the way you breathe at night? In this episode, recorded live at The Metabolic Health Summit, Dr. Jonathan Jun reveals how metabolism and sleep-disordered breathing are deeply connected, and why shifting from carbs to fat might improve more than just your waistline.

    Dr. Jonathan Jun, a leading researcher on obesity hypoventilation syndrome (OHS) and obstructive sleep apnea (OSA), walks us through the groundbreaking KETOHS trial, where a ketogenic diet was tested for its effects on carbon dioxide retention, sleep apnea severity, and metabolic health. The findings suggest ketosis may do more than promote weight loss - it could directly enhance respiratory efficiency and sleep quality in patients with OHS and OSA.

    From a long-forgotten 1976 fasting study to modern clinical data, this lecture reframes the connection between diet, breathing, and metabolism, revealing how nutritional ketosis might transform respiratory and metabolic medicine.

    Questions Answered in This Episode:

    • Why does fuel choice (carbs vs. fat) matter for breathing in people with sleep-disordered breathing?
    • What exactly happens in obesity hypoventilation syndrome (OHS), and why is it more dangerous than OSA alone?
    • Why did a 1976 starvation ketosis study inspire modern trials on ketogenic diets for OSA/OHS?
    • How was the KETOHS trial designed to isolate the effects of ketosis itself (not just weight loss)?
    • Can a ketogenic diet improve sleep apnea severity even without CPAP therapy?
    • Is the improvement in CO₂ clearance explained only by weight loss, or something else?
    • What metabolic changes accompany ketogenic therapy in this context?

    This episode will change the way you see the link between diet and breathing, and may open new doors for treating some of the toughest sleep and metabolic disorders.

    Special thanks to the sponsors of this episode:

    ✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here.
    ✅ ZocDoc - Find and instantly book a top-rated doctor here.
    ✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here.

    In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

    You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

    Find us on social:

    • Instagram
    • Facebook
    • YouTube
    • LinkedIn

    Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

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    47 mins
  • The Metabolic Approach to Treating Food Addiction | Dr. Tro Kalayjian | The Metabolic Link Ep. 77
    Oct 1 2025

    Could treating food like a drug be the breakthrough we've needed in food addiction treatment?

    In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Tro Kalayjian - physician, researcher, and former obesity patient - to explore whether food addiction should be classified as a true addiction, and how his TOWARD model is helping patients overcome binge eating and food-related compulsions.

    Dr. Tro shares findings from his recent peer-reviewed paper, TOWARD: a Metabolic Health Intervention That Improves Food Addiction and Binge Eating Symptoms. The study evaluated outcomes from the TOWARD intervention, a telemedicine-based model that combines metabolic nutrition, real-time biofeedback, and coaching. Nearly half of participants reduced food addiction symptoms, and over 80% saw improvements in binge eating - often independent of weight loss.

    This conversation explores the science of dopamine signaling, the failure of calorie-restriction models, the blurred line between food addiction and eating disorders, and how this approach could reshape treatment through scalable, real-world solutions.

    Questions Answered in This Episode:

    • How should we define food addiction compared to binge eating disorder?
    • Should ultra-processed food addiction be officially recognized in the DSM?
    • Why is food addiction harder to treat than drug or alcohol addiction?
    • What were the key outcomes of the TOWARD study on food addiction and binge eating?
    • Can lifestyle interventions compete with bariatric surgery or GLP-1 drugs?
    • How can employers scale food addiction treatment for high-risk populations?

    Check out Dr. Kalajian's TOWARD app here.

    Special thanks to the sponsors of this episode:

    ✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here!

    ✅Cowboy Colostrum - Get 25% offwhen you use code METABOLICLINK at checkout!

    ✅Piquelife.com - Get the Pu'er Bundle for 20% off here.

    In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!

    You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!

    Find us on social:

    • Instagram
    • Facebook
    • YouTube
    • LinkedIn

    Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

    Show More Show Less
    1 hr and 23 mins
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