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In this episode of The Incubator Podcast, we sit down with Dr. David Askenazi, Dr. Heidi Steflik, and Dr. Kimmy Vuong to explore the latest research and practice shifts in neonatal nephrology. The discussion begins with the often-overlooked role of the kidney in the NICU and why kidney health has direct implications for outcomes far beyond discharge.

The group reviews three recent high-impact papers. The first, a secondary analysis of the PENUT trial, examines whether PDA treatment in extremely low gestational age infants influences two-year kidney outcomes, raising questions about long-term renal risks and benefits of medical and surgical interventions. The second paper presents a consensus statement on kidney health monitoring for NICU graduates, offering structured recommendations on risk stratification and follow-up for preterm, critically ill, and cardiac infants. Finally, we highlight a quality improvement initiative that used the “Can You PLOTS” bundle to reduce ventilator days by addressing fluid overload systematically, underscoring the importance of early, proactive kidney-focused care.

This conversation emphasizes kidney disease as a critical factor in neonatal medicine, the growing pathways for neonatal nephrology training, and practical steps teams can take now to better integrate kidney health into NICU care.

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As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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Reducing NICU ventilator days by preventing fluid overload with the CAN-U-P-LOTS standardized bundle.

Askenazi DJ, Gordon L, Griffin R, Collins M, Black A, Ambalavanan N, Webb T, Mathis M, Short K, Umberger A, Travers C.Pediatr Res. 2025 Jul 11. doi: 10.1038/s41390-025-04078-x. Online ahead of print.PMID: 40646283

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

Enjoy!

Send us a text

Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates: A Modified Delphi Consensus Statement.

Starr MC, Harer MW, Steflik HJ, Gorga S, Ambalavanan N, Beck TM, Chaudhry PM, Chmielewski JL, Defreitas MJ, Fuhrman DY, Hanna M, Joseph C, Kwiatkowski DM, Krawczeski CD, Liberio BM, Menon S, Mohamed TH, Rumpel JA, Sanderson KR, Schuh MP, Segar JL, Slagle CL, Soranno DE, Vuong KT, Charlton JR, Gist KM, Askenazi DJ, Selewski DT; Neonatal Kidney Health Consensus Workshop.JAMA Netw Open. 2024 Sep 3;7(9):e2435043. doi: 10.1001/jamanetworkopen.2024.35043.PMID: 39269711 Free article.

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

Enjoy!