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The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

By: Dave Asprey
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About this listen

For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.

You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.

Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.

Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.

© Copyright © Bulletproof Media 2023 Hygiene & Healthy Living Personal Development Personal Success Science
Episodes
  • BONUS: How To Reverse Testosterone Decline After 40 (Biohacking Tips) : 1328

    BONUS: How To Reverse Testosterone Decline After 40 (Biohacking Tips) : 1328
    Sep 14 2025

    Most men think declining testosterone is just “part of aging”, but that’s a lie Big Pharma sold you. In this video, I break down exactly how I raised my testosterone in my 50s without injections, drugs, or TRT. These are the same biohacks I used to turn my energy, drive, and strength around, naturally. I’ll walk you through how your diet, your sleep, and even the light in your bedroom could be sabotaging your hormones. Want results? Start here.


    Chapters:

    0:00 – Introduction

    1:40 – The Lie About Aging and Testosterone

    2:49 – What’s Desatroying Your Testosterone Daily

    3:42 – How Your Cells Actually Make Testosterone

    4:58 – Why Diet is Step One (and What to Eat)

    7:08 – The Most Underrated T Booster

    8:38 – The Truth About Light and Hormones

    14:40 – How to Fix It


    Get Your Oral Testosterone Here: http://www.LiveThrive.co/asprey


    Connect with Dave Asprey!


    Website: https://daveasprey.com

    TikTok: https://www.tiktok.com/@daveaspreyofficial

    Instagram: https://www.instagram.com/dave.asprey/

    Facebook: https://www.facebook.com/Daveaspreyofficial/

    X: https://x.com/daveasprey

    YouTube: https://www.youtube.com/c/daveaspreybpr


    The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    16 mins
  • Eat THESE Anti-Aging Mushrooms to Live Longer (Paul Stamets) : 1327

    Eat THESE Anti-Aging Mushrooms to Live Longer (Paul Stamets) : 1327
    Sep 12 2025
    Want to biohack your biology with nature’s most powerful anti-aging compounds? In this episode, you’ll discover how medicinal mushrooms fuel neurogenesis, protect mitochondria, supercharge immunity, and even help save the planet’s pollinators. From sharper focus and deeper REM sleep to protecting DNA from oxidative stress, fungi are the ultimate biohacking tools for performance, resilience, and longevity. Watch episodes on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR (Re-run) Host Dave Asprey sits down with legendary mycologist and author Paul Stamets and mushroom entrepreneur Julian Mitchell. Together, they uncover the science of fungi as medicine — how mushrooms repair nerves, fight viruses, act as prebiotics for your microbiome, and provide the ultimate anti-aging biohacks. You’ll also hear how fungi hold the key to saving pollinators, regenerating soil, and extending human longevity. You’ll Learn: • Which anti-aging compounds in mushrooms protect your mitochondria and DNA • How lion’s mane stimulates nerve growth factor and improves memory, focus, and REM sleep • Why oyster mushrooms may help fight flu viruses and reduce chronic inflammation • How mushroom tinctures unlock more bioactive compounds than powders or capsules • The surprising role fungi play in saving bees and restoring environmental balance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: anti-aging mushrooms, Paul Stamets fungi, lion’s mane memory, mushroom tincture benefits, ergothionine mitochondrial protection, oyster mushroom flu prevention, reishi immune system, cordyceps endurance, turkey tail microbiome, medicinal mushroom research, fungi save the bees, chaga antioxidants, mushroom longevity biohack, mycelium networks, functional mushrooms anti-inflammatory, mushroom brain health, neurogenesis fungi, adaptogenic mushrooms, mushroom cooking bioavailability • Lifecykel Mushroom Products - use code ‘DAVE20’ for 20% off: https://www.lifecykel.com/?rfsn=4497217.61b030&utm_source=refersion&utm_medium=affiliate&am… • Paul Stamets’ Website: https://hostdefense.com/ Thank you to our sponsors! • ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources: • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 0:47 — Intro • 6:15 — Mushrooms vs. Algae • 10:21 — Mushroom Safety & Microbiome • 12:24 — Mushrooms as Medicine • 14:43 — Psychedelics & Microdosing • 16:26 — Kakadu Plum & Prebiotics • 18:07 — Oyster Mushrooms & Cooking • 21:35 — Mushrooms & Bees • 25:59 — Lion’s Mane & Chaga See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    31 mins
  • MIT Neuroscientist: The Ultimate Nootropic For Memory : 1326

    MIT Neuroscientist: The Ultimate Nootropic For Memory : 1326
    Sep 11 2025
    Want to improve memory, unlock neuroplasticity, and achieve sharper brain optimization? This episode reveals how Transcendental Meditation (TM) functions as one of the most powerful nootropics for human performance, longevity, and resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with neuroscientist and physician Dr. Tony Nader, the global leader of the Transcendental Meditation movement. With an MD and PhD from MIT and Harvard, Dr. Nader bridges hard science with ancient wisdom, showing how TM measurably changes brainwaves, boosts mitochondria, and even slows biological aging. His research connects meditation to reduced stress, faster reaction time, and improved memory, giving listeners cutting-edge tools for smarter not harder living. You’ll Learn: • How Transcendental Meditation induces high-coherence alpha brain states that improve clarity, focus, and resilience • Why TM increases blood flow to the prefrontal cortex and supports memory, decision-making, and creativity • How meditation measurably reduces biological age by 5–10 years through stress reduction and physiological balance • Why reaction time and situational awareness improve immediately after meditation — even used by fighter pilots • How TM differs from mindfulness or concentration practices at the brainwave level (alpha vs. theta vs. gamma) Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Transcendental Meditation benefits, Tony Nader MIT neuroscientist, TM brainwaves alpha coherence, Meditation and neuroplasticity, Default mode network meditation, Meditation and mitochondria, TM and biological age, Consciousness and quantum field theory, Meditation vs psychedelics, Meditation and intuition training, Meditation and dopamine, TM reaction time studies, Hippocampus meditation memory, TM and functional medicine, Meditation and metabolism, Meditation and PTSD recovery, TM for sleep optimization, Meditation and fasting stack, TM and human performance, Meditation and longevity research Thank you to our sponsors! Business of Biohacking Summit | Apply to The Business of Biohacking Summit https://businessofbiohacking.com/. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Tony’s Website: https://drtonynader.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:47 — Intro 2:57 — Transcendental Meditation 3:56 — States of Consciousness 10:16 — Brainwaves & Practice 18:35 — Science Bias 38:07 — Mind & Reality 50:32 — Psychedelics & TM 54:29 — Brain & Body Effects 59:31 — Daily Practice 1:02:43 — Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    1 hr and 4 mins
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