On the Square Circle Podcast, Dr Jordan Abdi, physician and CEO of U-Ploid, a fast-growing biotech developing treatments to help women extend and expand their reproductive window by improving egg quality.

This conversation goes deep into fertility science, biotech risk, IVF realities, stigma, and the potential future of reproductive medicine.

⏱️ TOP CHAPTERS — The Key Moments

00:00 – Welcome to Square Circle

00:37 – Introducing Dr. Jordan Abdi

01:30 – Jordan’s journey: NHS → biotech → fertility

03:19 – Why reproductive health is decades behind other fields

05:48 – What U-Ploid is building (and why it matters)

09:36 – The fertility crisis: $35B IVF market, 70% failure rate

12:24 – Extending the reproductive window: what is actually possible

14:35 – The real cause of declining egg quality (explained simply)

17:26 – Why IVF fails in women 35–45 (chromosome errors)

18:56 – The emotional and social stigma around fertility

20:39 – Fertility is NOT a women-only issue

23:05 – Fundraising & biotech: how it really works

27:32 – The regulatory and safety challenges in reproductive biotech

30:43 – Advisory board vs governance board: what founders must know

33:41 – The biggest lessons Jordan learned building U-Ploid

35:25 – When could these treatments reach the market?

37:47 – Closing reflections & message to listeners

💡 What You'll Learn

• Why IVF outcomes decline so sharply after 35

• The biological reason behind miscarriages & failed embryos

• What "egg quality" actually means (in plain English)

• The science behind U-Ploid’s lead treatment, Livanta

• How biotech startups manage multi-year risks

• How fertility stigma harms both men and women

• Why the UK is a global leader in reproductive innovation

• What founders should know before entering biotech

📩 Want to join the community, be a podcast guest, or sponsor an episode?

Email Mario Rivas → mario@squarecircle.life

📩 Want to join the LinkedIn community? https://www.linkedin.com/company/square-circle-startup-and-scale-up-people/?viewAsMember=true

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