In this episode, Dr. Datis Kharrazian explains what happens to our muscles as we age and why maintaining muscle mass is crucial for mobility, bone density, cognition, metabolic and immune health, and recovery from chronic illness. You’ll hear actionable insights about sarcopenia (age-related muscle loss), the muscle-gut connection, the power of myokines, and how hormones, nutrition, and strategic exercise can make a life-or-death difference.

You’ll hear evidence-based guidance on protein intake, key nutrients, common causes of dysfunctional muscle metabolism, and how to identify and address issues like statin-induced myopathy and abnormal muscle tone.

To dive deeper, enroll in the Kharrazian Institute’s Degenerative Joint, Muscle, and Bone Conditions Course.

Sign up here: https://pages.kharrazianinstitute.com/ki-bone-joint

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 "Muscle Mass Essential for Longevity"

03:05 Sarcopenia Significantly Increases Mortality Risk

08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise

10:56 Gut-Muscle Axis: Impact on Fitness

13:09 Gut-Muscle Connection: Sarcopenia Insights

17:33 Muscle Metabolism and Protein Sufficiency

20:02 Protein Intake Crucial for Muscle Maintenance

25:30 Muscle Issues: Causes and Solutions

27:26 Creatine: Muscle Boost and Benefits

32:19 Accelerated Muscle Aging Process

35:52 Improving Muscle Metabolism with Autophagy

38:58 Statins Linked to Muscle Dysfunction

40:00 Statin Impact on Muscle Health

43:08 Trigger Points and Myofascial Pain

48:17 Myofascial Syndromes and Muscle Dysfunction

52:52 Functional Medicine Training and Resources

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

In this episode, you’ll learn how movement directly influences your metabolism, immune system, brain function, and even the diversity of your gut microbiome. Dr. Kharrazian explains the critical role of messenger proteins released during physical activity, why maintaining muscle mass and bone density is key to longevity, and how inflammation can undermine your body’s ability to recover.

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 Introduction to the Podcast

00:30 How Physical Movement Impacts Health

01:54 Bone Volume, Osteopenia, and Health Consequences

02:56 Toxic Chemicals, Bone Loss, and Aging

03:50 Muscle Mass, Sarcopenia, and Mortality

04:38 Movement, Depression, and Brain Chemistry

05:15 Movement, Myokines, and Immune Function

05:59 Microbiome Diversity, Gut Health, and Inactivity

06:32 Overtraining Syndrome and its Red Flags

07:11 Exercise, Mitochondrial Health, and Chronic Disease

07:49 Movement & Brain Health: Repair, Mood, and Cognitive Disorders

08:25 Sedentary Lifestyle in Children & Sarcopenia Risks

09:45 Medical Management of Osteoporosis and Arthritis

10:55 Inflammation, Muscular and Skeletal Degeneration

12:16 Body Fat, Skinny Fat, and Inflammation

12:46 Insulin Surges and Systemic Inflammation

13:31 Microbiome, Leaky Gut, and Chronic Inflammatory Disease

16:04 Food, Environmental Toxins, and Inflammation

18:09 Protein Intake and Recovery from Chronic Disease

19:12 Sleep, Sleep Apnea, and Bone Health

19:57 Regenerative Medicine Therapies

21:34 Conclusion and Podcast Resources

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Welcome back to Solving the Puzzle with Dr. Datis Kharrazian, the podcast where evidence-based functional medicine meets real-world application. In this episode, Dr. Joseph Pizzorno, a pioneering voice in environmental medicine and toxicology dives into the hidden world of environmental toxins—discussing the staggering number of chemicals we're exposed to every day, why testing for toxins can be more complex than most realize, and which common exposures may be silently sabotaging our health.

Dr. Pizzorno reveals the challenges in accurately measuring toxic load, the wide differences in our bodies’ abilities to detoxify, and why focusing on exposure and biological damage is often more useful than hunting for specific chemicals in the blood or urine. You'll learn about practical strategies for identifying and reducing toxin exposure, the synergistic effects of multiple chemicals, and simple steps you can take to support your body’s natural defenses.

Whether you're a clinician wanting clinical pearls or someone seeking to optimize your health in an increasingly toxic world, this episode will empower you with the knowledge and tools to take action.

For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/

For patient-oriented courses, visit https://drknews.com/online-courses/

For CE and CME practitioner courses, visit https://kharrazianinstitute.com/

00:00 Assessing Exposure and Detox Challenges

03:37 "Assessing Synergistic Environmental Toxins"

07:09 "Toxic Load vs. Disease Correlation"

11:24 Tea Habits and Water Concentration

16:24 Chemical Impact on Neurological Health

17:48 Persistent Human-Made Molecules

23:20 Bisphenols Lowering Children's IQ

26:18 Chemical Food Sources & Glyphosate Exposure

28:26 Cerrillini's Impact on Glyphosate Regulation

32:50 "Assessing Kidney Toxicity via EGFR"

36:44 "Enhancing Body Detoxification"

37:42 "Detox Strategy: Sweat and Monitor"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.