The future of AI-enabled care is massive and available, but the question remains: will we be the ones leading it?

In this episode, Dr. Robert Pearl – Former CEO of Permanente Medical Group (Kaiser Permanente), Author of "ChatGPT, MD", Forbes Contributor – joins the panel to challenge the core of how we practice medicine today. Medical students are entering training with AI capabilities that their professors don't possess. But beneath this technological evolution lies a clinical crisis: 400,000 deaths annually from misdiagnosis, intermittent care for chronic diseases, and a system that could eliminate up to $2 trillion in wasteful spending.

The conversation addresses why AI integration advances rapidly in other countries, yet the US lags, not from lack of technology, but from cultural resistance and misaligned financial incentives. Dr. Pearl reveals the solution he's witnessed work at scale that allows a delivery system to have smarter chronic disease management and better doctor-patient interaction.

This discussion connects directly to what matters most in clinical practice: better diagnostic accuracy, continuous disease monitoring that actually works, and care delivery that doesn't burn out physicians while delivering superior results. The paradigm can shift from the traditional trade-off between quality, access, and cost to a model where increasing quality and access genuinely lowers cost.

What You Will Discover:

- The Era of Smarter Students: AI Skills Professors Don't Have

- The Clinical Crisis: 400,000 Deaths From Misdiagnosis

- How 24/7 AI Monitoring Reduces Heart Attacks & Strokes by 30-50%

- Why Current Incentives Block AI Adoption

- The Fee-for-Service Problem: Rewarding Volume Over Outcomes

- Why Singapore & Dubai Lead While the US Lags

- The Capitation Solution: Evidence From Kaiser's Model

- Flipping the Paradigm: Lower Cost Through Higher Quality & Access

Referenced in the show:

🖇️ "ChatGPT, MD: How-AI Empowered Patients & Doctors Can Take Back Control of American Medicine" – https://www.amazon.com/dp/B0CWCV9DVZ

🖇️ “Mistreated: Why We Think We’re Getting Good Health Care – And Why We’re Usually Wrong” – https://www.amazon.com/Mistreated-Think-Getting-Health-Usually/dp/1610397657/

Connect with us:

Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

🔗Website - https://www.junaidkalia.com/

📹YouTube - https://www.youtube.com/@junaidkaliamd

Dr. Harvey Castro, ER Physician, #DrGPT™

💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

🔗Website - https://www.harveycastromd.com/

📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

Edward Marx, CEO, Advisor

💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

🔗Website -

If healthcare AI is truly evolving, why are there still gaps between what technology can do and what healthcare organizations are actually doing? These gaps aren't just inefficiencies. They're creating real clinical risks that directly impact patient outcomes.

This year-end roundtable brings together three healthcare AI experts—Dr. Harvey Castro, Dr. Junaid Kalia, and Edward Marx—following their appearance at AIMed 2025 to share their key takeaways from deploying AI in the messy reality of hospital systems. They synthesize insights across policy, culture, and implementation: how cost disruption reshapes hospital innovation budgets, what Singapore's mandatory retraining model signals about workforce transformation, and where CMS guidelines create strategic inflection points for health systems. They demonstrate what continuous collaborative learning looks like in practice: completing advanced certifications, testing tools hands-on in their own workflows, and building AI systems for acute care environments.

Whether you're a clinician evaluating AI tools for your practice, an executive planning institutional strategy, or a founder building healthcare AI solutions, this episode helps you separate signal from noise and position yourself strategically in this transformation.

What You Will Discover:

- Introduction & ABIM Course Discussion

- Ed's 3 Key Learnings for AI-Driven Transformation

- Harvey's 3 Takeaways: Martec's Law & The Culture Problem

- Junaid's 3 Lessons from Building AI Solutions

- Why Nurses Are Being Left Behind in AI Adoption

- Deep Seek Impact: How AI Costs Dropped 99%

- Who Should Pay for AI? Government vs. Private Investment

- Singapore's Approach: Mandatory AI Retraining Policy

Referenced in the show:

🖇️ “2025 Agenda: Advancing Healthcare with Expert-Led AI” – https://aimed.swoogo.com/aimed25/8350420

Connect with us:

Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

🔗Website - https://www.junaidkalia.com/

📹YouTube - https://www.youtube.com/@junaidkaliamd

Dr. Harvey Castro, ER Physician, #DrGPT™

💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

🔗Website - https://www.harveycastromd.com/

📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

Edward Marx, CEO, Advisor

💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

🔗Website - https://www.marxadvisory.com/

📹YouTube - https://www.youtube.com/@EdwardMarx

Visit our website:

https://signalandsymptoms.com/

Get advisory insights about...

Innovation signals are everywhere, but what matters are those that move from laboratory potential to measurable clinical impact.

Joining the conversation are Jim Pollock and Tom Meese from LumenAstra, demonstrating how clinical insight, technical capability, and strategic execution bridge the gap between healthcare innovation and patient outcomes. The discussion explores how their innovative work in developing non-invasive internal body temperature measurement technology will transform the future of AI development, enhance predictive models, and drive the creation of new clinical applications, all while leveraging the interdisciplinary nature of healthcare technology.

This isn't promotional & theoretical. Just the evidence of what happens when we measure the right interventions and act on them wisely.

What You Will Discover:

- Introduction to Lumen Astra & Its Mission

- Innovative temperature measurement technology

- Why has technology only emerged now

- How real-time brain temperature improves clinical decisions

- Dr. Kalia's compassion fatigue story in Neuro-ICU

- Building through customer discovery over assumptions

- Closing: AI, evidence, and future

Connect with us:

Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

🔗Website - https://www.junaidkalia.com/

📹YouTube - https://www.youtube.com/@junaidkaliamd

Dr. Harvey Castro, ER Physician, #DrGPT™

💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

🔗Website - https://www.harveycastromd.com/

📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

Edward Marx, CEO, Advisor

💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

🔗Website - https://www.marxadvisory.com/

📹YouTube - https://www.youtube.com/@EdwardMarx

Connect With Our Guests:

Jim Pollock - Co-founder, LumenAstra

💼LinkedIn - https://www.linkedin.com/in/jipollock/

Tom Meese - Co-founder, LumenAstra

💼LinkedIn - https://www.linkedin.com/in/tom-meese-615ab35/

For clinical collaboration or investment inquiries

📧

🔗- https://www.lumenastra.io/

Visit our website:

https://signalandsymptoms.com/

Get advisory insights about Healthcare AI — at zero cost: