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Can a nerve regenerate without surgery?
This case suggests yes.

In this episode of Pod of Inquiry, Dr. Stephen Barrett sits down with Dr. Erin Nelson to review a rare EMG-documented case of nerve regeneration after ultrasound-guided Hydrodissection with D5W — no scalpel required.

A 56-year-old woman developed sudden foot drop due to deep peroneal nerve entrapment. After two D5W Hydrodissection sessions, a 4-month repeat EMG showed significant interval improvement in demyelination + axonal injury. Objective. Measurable. Independent neurologist confirmed.

🎯 What you'll learn in this episode:
• Why 5% dextrose (D5W) outperforms saline in Hydrodissection
• The exact protocol Dr. Nelson uses (volume, frequency, technique)
• When to choose Hydrodissection vs. surgical decompression
• Implications for patients with diabetic neuropathy
• The difference between glucose puncture vs Hydrodissection

This may become one of the most important clinical conversations in the nerve pain / peripheral neuropathy space.

Visit our website https://podofinquiry.com/latest-episodes/ - click on the show link to read the show notes and get more information.

Timestamps:
00:00 - Introduction
00:52 - Opening & Welcome
02:39 - What is Hydrodissection?
04:03 - Why D5W Over Other Solutions?
05:33 - Safety in Diabetic Patients
07:12 - Safety Profile & Substance P
07:50 - Glucose Puncture vs Hydrodissection
09:48 - Case Presentation Begins
10:00 - Patient History
13:47 - Prior Upper Extremity Surgeries
17:09 - EMG Findings
18:17 - Weight Loss Connection
19:24 - Physical Examination
22:59 - First Hydrodissection
23:03 - One Month Follow-up
23:16 - Second Hydrodissection
25:45 - EMG Improvement
26:33 - Significance of Objective Findings
27:06 - Current Status
30:19 - Causes of Nerve Entrapment
31:48 - Hydrodissection Mechanism Review
33:20 - Patient Experience
34:41 - Future Considerations
36:39 - Conservative Approach Benefits
39:39 - Residual Symptoms & Central Sensitization
41:04 - Complexity of Treatment
42:17 - Contact Information

-- Hashtags --
#D5WHydrodissection #NerveRegeneration #Electrodiagnostics #EMG #Neuropathy #PeripheralNerve #UltrasoundGuidedProcedures #PainMedicine #RegenerativeMedicine