Reduced Brain Activity and Cognitive Impairment in Sleep Apnea
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Reduced Brain Activity and Cognitive Impairment in Sleep Apnea
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About this listen
This episode investigates the relationship between Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) and cognitive impairment by examining changes in brain activity. Using resting-state functional MRI (rs-fMRI), the study compared brain activity in severe OSAHS patients to healthy individuals, analyzing Regional Homogeneity (ReHo) and fractional Amplitude of Low-Frequency Fluctuation (fALFF) values. The findings indicate that OSAHS patients exhibit altered brain activity in specific regions, correlating with reduced cognitive function as measured by MoCA scores. Furthermore, the identified abnormal brain regions proved effective in distinguishing OSAHS patients from healthy controls, offering insights into the neurological mechanisms underlying OSAHS-related cognitive deficits.