Episodes

  • Episode 585 - Jeff Zenisek
    Nov 14 2025

    Comedian Jess Zenisek (@jeffzenisek) joins Andy, Jesse and Matt to talk about tennis, homophobic sports stereotypes, Jesse's new ski persona, Mr. Wizard, Jeff's hair care regimen, a tiny tyrannosaur, a better rock-paper-scissors strategy, gray hair's relationship to cancer, the worst music to play during sex and the banger Parked By The Lake.

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    1 hr and 12 mins
  • Episode 584 - Drew Droege
    Nov 10 2025

    Comedian/playwright Drew Droege (@drew_droege) joins Matt, Jesse and Andy to talk about his new off-Broadway play Messy White Gays, X-ray NBA poker fraud and why birds sing after a solar eclipse.

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    52 mins
  • Episode 583 - Mehran Khaghani
    Oct 29 2025

    Wonderful NY comic Mehran Khagani (@themehran) joins Jesse and Matt to talk about escaping from Iran, working at the Harvard School of Public Health, hyrax butt drag fossil marks, Canadian heart transplants and the most pristine star in the universe!

    In the patreon bonus we get into penguin micronaps.

    Click here to support Probably Science via Patreon

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    54 mins
  • Episode 582 - Jen Kober
    Oct 20 2025

    Comedian/actor Jen Kober (@jenkober) joins Andy, Jesse and Matt to talk about comedy in Louisiana, Oktoberfest, buxom wenches, the connection between fish buttholes and fingers, a koala chlamydia vaccine, Jesse's newfound raccoon fame, light-powered gears that fit inside a strand of hair and Jen's membership in the Star Wars canon.

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    1 hr and 12 mins
  • Episode 581 - NASA Exoplanet Science Ambassador Anjali Tripathi
    Oct 5 2025

    NASA astrophysicist and JPL Exoplanet Science Ambassador Anjali Tripathi joins Andy, Jesse and Matt to talk about exoplanets and the different ways of finding them including radial velocity, transits and gravitational microlensing, the challenges of studying planetary atmospheres, why telescopes are built in deserts or in space, Anjali's time at the White House Office of Science and Technology Policy, science communication projects like the Logic 44ever rap video, the upcoming Nancy Grace Roman Space Telescope, dark matter, lasers in astronomy, Halloween at the White House, the odd "smells" of other planets and how to take a virtual tour of JPL.

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    1 hr and 21 mins
  • Episode 580 - Michelle Murphy
    Sep 27 2025

    Comedian Michelle Murphy (@meeshoffleash) joins Andy, Matt and Jesse to talk about playing tennis for Grinnell, the Enhanced Games, celebrities trying their hands at winter sports, Jesse's accidental mermaid book purchase and the Dr. Seuss book he was aiming for, Burning Man missionaries, LSD to fight anxiety and surprisingly not too uncommon iridescent mammals.

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    1 hr and 21 mins
  • Episode 579 - Ken Reid
    Sep 17 2025

    Comedian Ken Reid (@kennethwreid) joins Jesse, Matt and Andy to talk about growing up a child of television, mud wrestling, Ken's podcast TV Guidance Counselor, an HIV prevention breakthrough, the insanity of Movie 43, the human washing machine no one asked for, blasting plastic waste with a plasma torch, Doja Cat's nod to Max Headroom, Ladies and Gentlemen, The Fabulous Stains, the reason plastic recycling mostly ended, Andy's Oktoberfest shows in Lake Arrowhead and John Williams polka music.

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    1 hr and 16 mins
  • Episode 578 - Ryan O'Flanagan
    Sep 9 2025

    Comedian Ryan O'Flanagan (@ryanoflan) joins Matt, Jesse and Andy to talk about Ryan and Andy's chance encounter in a bar in Leadville, Married With Children tattoos, neanderthals and homo sapiens interbreeding, a novel telescope shape to help search for exoplanets, an insane impression of a neanderthal voice and Ryan's podcast Laser Show.

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    1 hr and 12 mins