Episodes

  • Andrew Ng on winning the AI race, with DJ Patil
    Nov 26 2025

    Andrew Ng has been a leading voice in AI for over a decade. As Managing General Partner at AI Fund, and co-founder of Coursera and DeepLearning, among other roles, Ng has shaped the modern AI landscape and spread AI education to the masses. Onstage at this year’s Masters of Scale Summit, he sat down with former US Chief Data Scientist and now General Partner at GreatPoint Ventures, DJ Patil, to discuss the state of AI today and the true potential of everything placed under the “agentic” umbrella. Together, they unpack what it will take for America to stay competitive in the global AI race and why it’s still important to know how to code.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    24 mins
  • Mark Cuban’s investment strategy in the world of AI
    Nov 19 2025

    Mark Cuban has spent decades as a serial entrepreneur and investor, with one of the best track records on the planet (including celebrity status on ABC’s Shark Tank). His success stems in part from an ability to spot opportunity early — and now he’s bringing that approach to AI. Cuban is backing AI companies that he sees taking bold swings and reimagining how we live. He joins Pioneers of AI for a wide-ranging conversation about whether we are in an AI bubble, how he’s applying his investment philosophy to AI, and why the AI world is tending to excite him less and less each day.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    40 mins
  • Possible: Lisa Su on semiconductors, compute, and big bets
    Nov 15 2025

    What’s the role of semiconductors—and the companies that make them—in powering human progress? What does it look like to innovate thoughtfully in a landscape where the demand for power may be higher than the supply? With AI evolving faster and faster, how can we keep up?

    Advanced Micro Devices (AMD) CEO Lisa Su joins the show to talk about hardware, global manufacturing, and risk-taking. She shares what she has learned leading AMD from near-bankruptcy a decade ago to its current standing as one of the world’s leading chipmakers. Lisa also weighs in on geopolitics, the AI arms race, startups, what makes her want to hire someone, and AI’s enormous potential to advance healthcare for humankind.

    For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    43 mins
  • How AI can unlock life-saving cures, with Siddhartha Mukherjee
    Nov 12 2025

    Discovering new medicines has long been a slow, inefficient, and expensive process. Siddhartha Mukherjee, esteemed cancer biologist and author of the Pulitzer Prize-winning book The Emperor of All Maladies, is looking to change that. That’s why he partnered with Reid Hoffman to found Manas AI, a company that uses AI to accelerate drug discovery and develop life-saving cures faster and cheaper. He joins Pioneers of AI to discuss which parts of the drug development process are transformed by AI, how generative AI tools based on physics and chemistry differ from other LLMs, and why creating Manas AI was a leap of faith.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    29 mins
  • Designing AI for people and the planet, with Aza Raskin
    Nov 5 2025

    AI is rapidly changing what it means to be human, but is AI development truly human-centered? According to Aza Raskin, co-founder of the Center for Humane Technology, the answer is largely “no.” The man who invented the “infinite scroll” is now working to understand why the most powerful technology so often fails to prioritize the human experience and our collective well-being. Raskin is also leading the Earth Species Project — using AI to better understand the animals that live alongside us, by unlocking patterns in vast amounts of data on animal communication. He joins Pioneers of AI to talk about both of these dynamic endeavors, with the flourishing of humans and Earth at the core.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    45 mins
  • Baratunde Thurston wants us to reimagine our relationship with AI
    Oct 29 2025

    How we decide to live with AI, at home or at work, will greatly impact our personal and professional futures. Baratunde Thurston, a comedian, writer, and commentator, has had a long career exploring what a harmonious relationship between human beings and our machines could look like. Now, as host and co-creator of the podcast Life with Machines, he explores what it means to live and collaborate well with AI, by talking with the people helping to shape our new reality. Thurston joins Pioneers of AI for a dynamic conversation about Life with Machines’ first year, building and working with the show’s AI-producer named Blair, and how AI should help us reconnect with our own humanity.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    37 mins
  • Could this be the future of K-12 education?, with Alpha School’s Joe Liemandt
    Oct 22 2025

    Educators around the world are wrangling with AI in learning. At Alpha School, a private K-12 school based in Texas, students use AI-driven software to complete core subjects in about two hours’ time. They spend the rest of the school day with guides for social-emotional learning, project-based work, and life skills. Joe Liemandt, longtime software developer and investor, serves as the principal of Alpha School. Dr. Rana el Kaliouby joined him on stage at this year’s Masters of Scale Summit, along with Alex Matthew, an Alpha School high schooler. They discuss what students need to be prepared for the future, and the challenges in scaling Alpha School’s model.

    You can find all the Masters of Scale Summit stage sessions on our YouTube channel: https://www.youtube.com/playlist?list=PL4Tp7I0LquJtwF7CEU-B5sm7Eyuk3Aqma

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    25 mins
  • Vibe coding and the one-person startup, with Lovable's Anton Osika
    Oct 15 2025

    “Vibe coding” is taking software development by storm, allowing users to build apps by simply chatting with AI. These tools will transform how digital products and companies are created – and who gets to create them. Anton Osika is the co-founder and CEO of Lovable, a vibe coding platform that’s garnered a reported $4 billion valuation since its founding in 2023. Host Dr. Rana el Kaliouby sat down with Osika live on stage at this year’s Masters of Scale Summit to discuss how vibe coding is rewriting the rules of creation and democratizing access to entrepreneurship, and how it will impact software engineering and computer science in the future.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    21 mins