Episodes

  • Calculating Drug Dosages: A Patient-Safe Approach to Nursing and Math

    Calculating Drug Dosages: A Patient-Safe Approach to Nursing and Math
    Oct 24 2025
    Focused on safe and accurate drug dosage calculations for nursing and healthcare professionals. The material covers critical aspects of medication administration, emphasizing patient safety through adherence to guidelines like the Six Rights of Medication Administration. Key topics include systems of measurement (metric and household), dosage calculation methods (ratio and proportion, dimensional analysis, and formula), and the verification of medication orders, particularly for oral, parenteral (injections), and intravenous (IV) routes. Furthermore, the text addresses special considerations for vulnerable populations, such as pediatric and geriatric patients, and the importance of understanding drug-specific warnings like REMS and Black Box Warnings, alongside professional practices like labeling reconstituted medications and titrating IV drips.
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    15 mins
  • Cardiac Drugs

    Cardiac Drugs
    Oct 24 2025
    A comprehensive overview of pharmaceutical treatments for various cardiovascular conditions. The sections cover a wide array of topics, including the management of acute coronary syndromes (ACS), the use of antiarrhythmic drugs (AADs) to treat dysrhythmias, and detailed pharmacotherapy for heart failure (HF), including the role of neurohumoral modulation and positive inotropic drugs like dobutamine. Furthermore, the source provides extensive information on antihypertensive drugs, detailing classifications, dosing, and use in special populations like those with chronic kidney disease (CKD) and diabetes, alongside treatments for dyslipidemias using statins, fibrates, and niacin, and drug therapy during pregnancy and lactation. Finally, a concluding section briefly explores future directions in drug therapy, specifically highlighting the role of genetics and rare variants in developing new cardiovascular medications.
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    16 mins
  • Cardiac Drug Therapy

    Cardiac Drug Therapy
    Oct 24 2025
    Focusing on the pharmacological management of cardiovascular diseases. The content provides detailed coverage of various classes of cardiac medications, including Beta-Blockers, ACE Inhibitors, Calcium Antagonists, and Diuretics, often dedicating sections to controversies surrounding their use. Furthermore, the text addresses the Management of Angina, Acute Myocardial Infarction, Heart Failure, Cardiac Arrhythmias, and Dyslipidemias, offering advice on dosages, contraindications, adverse effects, and drug interactions, particularly in special populations like pregnant and lactating women. Finally, it frequently references and analyzes data from Hallmark Clinical Trials to support therapeutic recommendations and guide best practices for cardiologists, internists, and other healthcare providers.
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    13 mins
  • Cardiology Emergencies

    Cardiology Emergencies
    Oct 24 2025
    A comprehensive overview of cardiology emergencies, functioning as a handbook for medical professionals like residents and emergency physicians. The text covers a broad spectrum of acute cardiac conditions, including chest pain, syncope, heart failure, and life-threatening events like acute coronary syndromes and cardiac collapse, detailing their presentation, investigation, and management. It also addresses specialized topics such as valve disease, pericardial disease, and cardiac issues in specific populations like pregnant women and adults with congenital heart disease. Furthermore, the source includes guidance on practical procedures, such as central venous line insertion and cardioversion, and includes important disclaimers emphasizing that the material is not a substitute for professional medical advice due to the constantly evolving nature of medical knowledge.
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    15 mins
  • Cardiology Clinics

    Cardiology Clinics
    Oct 24 2025
    A comprehensive overview of advancements in drug therapies for cardiovascular disease and related conditions, emphasizing the shift toward pharmacologic prevention and management over procedural interventions. The articles discuss new or optimized drug classes aimed at improving patient outcomes, including Angiotensin Receptor Blockers (ARBs) and direct renin inhibitors for the renin-angiotensin-aldosterone system (RAAS), new antiplatelet agents like prasugrel, and anticoagulants for acute coronary syndromes. Furthermore, the texts examine novel strategies for lipid modification, such as CETP inhibitors and extended-release niacin combined with laropiprant to mitigate flushing, and explore the role of Dipeptidyl Peptidase-4 (DPP-4) inhibitors for managing Type 2 Diabetes Mellitus, a major cardiovascular risk factor. Finally, there is an analysis of the cardiovascular risks associated with cyclooxygenase-2 (COX-2) inhibitors (coxibs) in comparison to traditional NSAIDs.
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    17 mins
  • Cardiovascular Problems in Emergency Medicine: A discussion-based review

    Cardiovascular Problems in Emergency Medicine: A discussion-based review
    Oct 24 2025
    A comprehensive review of various critical cardiac conditions encountered in the emergency department, presented in a discussion-based format involving several attending physicians and residents. The text covers the diagnosis and management of acute coronary syndromes (ACS), including myocardial infarction (MI) and unstable angina, detailing diagnostic tools like EKGs, cardiac markers, and CT angiography. Additionally, the sources examine the evaluation and treatment of cardiac dysrhythmias such as bradycardia and atrial fibrillation, along with life-threatening conditions like aortic dissection, valvular heart disease, acute heart failure, and pericarditis/myocarditis. Crucially, the material includes legal disclaimers emphasizing that the content is for educational purposes and should not replace individualized medical judgment, while also providing acknowledgments to those who contributed to the book.
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    20 mins
  • Drugs for Pregnant and Lactating Women

    Drugs for Pregnant and Lactating Women
    Oct 24 2025
    An extensive reference guide focusing on the safe use of various drugs during pregnancy and lactation, specifically tailored for healthcare providers. For each medication, the text details aspects such as Drug Class, Indications, Mechanism, and Dosage, often including international brand names. Crucially, it provides Fetal Considerations and Breastfeeding Safety information, frequently noting the lack of adequate human studies and referencing animal data or observational cohorts, as seen with acetaminophen and its potential link to developmental issues. Furthermore, the text consistently assigns a Summary Pregnancy Category (e.g., C, D, X) and Lactation Category and outlines Drug Interactions for many agents.
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    18 mins
  • Cell Therapy Against Cerebral Stroke: Comprehensive Reviews for Translational Researches and Clinical Trials

    Cell Therapy Against Cerebral Stroke: Comprehensive Reviews for Translational Researches and Clinical Trials
    Oct 24 2025
    Highlighting the current state of translational research and clinical trials. The texts establish that conventional stroke treatments have reached a **therapeutic plateau**, making regenerative medicine, particularly cell transplantation, a crucial area of investigation. Specific cell types are discussed, including **Bone Marrow-Derived Mononuclear Cells (BMMNCs)**, **Mesenchymal Stem Cells (MSCs)**, and **Neural Stem Cells (NSCs)**, detailing their mechanisms of action, such as promoting angiogenesis, modulating inflammation, and inducing endogenous repair. The sources also analyze critical practical aspects for clinical application, such as the **optimal transplantation route, cell dose, and timing**, and the necessity of **functional bio-imaging** techniques and **biomaterial scaffolds** to enhance cell survival and efficacy.
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    21 mins