Ozempic Alzheimer's Trials Reveal Promising Biomarkers, No Cognitive Decline Improvement
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About this listen
In this eye-opening episode of Navigating Ozempic, we examine the groundbreaking EVOKE and EVOKE Plus trials testing semaglutide's effects on Alzheimer's disease. Despite Ozempic's remarkable $18.59 billion in global sales and unprecedented GLP-1 research activity in 2025, these Phase 3 trials delivered surprising results. While the medication improved certain Alzheimer's biomarkers, it failed to slow cognitive decline compared to placebo in over 3,800 participants with mild cognitive impairment or early-stage Alzheimer's.
We explore why researchers pursued this connection between GLP-1 medications and neurodegenerative diseases, what the results mean for current Ozempic users, and how this affects the expanding landscape of GLP-1 research. Learn why 16.4% of all global medical trials currently focus on GLP-1 medications, with Eli Lilly and Novo Nordisk leading innovation in this rapidly evolving field.
#Ozempic #GLP1 #AlzheimersResearch #WeightLossMedication #DiabetesTreatment #PharmaceuticalNews #MedicalTrials #NovoNordisk #CognitiveHealth
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