Episodes

  • Adrian Woolfson, "On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence" (MIT Press, 2026)

    Adrian Woolfson, "On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence" (MIT Press, 2026)
    Apr 20 2026
    Imagine a future where we grow houses rather than build them. Where smartphones are alive, clothing has opinions and all human knowledge fits into a speck of DNA. A world where disease is a thing of the past and the human lifespan is dramatically extended.To achieve this, says Adrian Woolfson, founder of the genome writing company Genyro, we must transform biology into a predictive, programmable engineering material. That means decoding the generative grammar of DNA: the language of life itself. We will then be able to author genomes—and, if we choose, even rewrite our own.In On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence (MIT Press, 2026), Woolfson describes how we are at the cusp of a technological revolution, driven by the convergence of artificial intelligence and synthetic biology. Currently at the scribbling phase—writing the genomes of viruses, bacteria and yeast—we will eventually author the genomes of extinct and never-before-realized species. Life will become computable, detached from its past and no longer bound by Darwinian evolution.While offering extraordinary opportunities, this power also carries great risk, and it is vital for everyone to understand what the future might hold. In this groundbreaking work, Woolfson provides a guide to this bold new world, offering a moral compass to help us do so safely, wisely and ethically. Adrian Woolfson is the cofounder of Genyro, a California-based biotechnology company specializing in synthetic genome design and construction. He studied medicine at Balliol College, Oxford, and was formerly the Charles and Katherine Darwin Research Fellow at Darwin College, Cambridge, working at the MRC Laboratory of Molecular Biology. Greg is the Executive Director and Founder of the World War II Discussion Forum (wwiidf.org). He also has a strong interest in literature, culture, religion, science and philosophy (translation: he's an eclectic reader who is constantly missing deadlines for book reviews). Learn more about your ad choices. Visit megaphone.fm/adchoices
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    55 mins
  • Beans Velocci, "Sex Isn't Real: The Invention of an Incoherent Binary" (Duke UP, 2026)

    Beans Velocci, "Sex Isn't Real: The Invention of an Incoherent Binary" (Duke UP, 2026)
    Apr 11 2026
    In Sex Isn’t Real: The Invention of an Incoherent Binary (Duke UP, 2026), Beans Velocci traces the history of current high stakes attempts to define sex and to create a world devoid of trans life. Drawing on lab notes, family genealogies, medical case studies, and more, Velocci follows scientists and clinicians from the mid-nineteenth through the mid-twentieth century and across five disciplines—zoology, eugenics, gynecology, statistical sexology, and transsexual medicine—as their ideas and practices created a definitional tangle. They demonstrate how the sorting of bodies into male and female persists not despite but because of sex’s incoherence: the defining features of these categories shift to contain various understandings of anatomy and physiology, theories of race, developments in research and medical methodologies, and bodies that cannot be accounted for in a binary framework. Exposing the endless work required to produce a world in which most people have a binary gender identity that neatly fits their binarily sexed body, Velocci demonstrates that it is not cis people who fit the categories; it’s the categories that flex to make them fit. Beans Velocci is Assistant Professor of History and Sociology of Science and Gender, Sexuality, and Women’s Studies at the University of Pennsylvania. Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr and 22 mins
  • Kathryn Nave, "A Drive to Survive: The Free Energy Principle and the Meaning of Life" (MIT Press, 2025)

    Kathryn Nave, "A Drive to Survive: The Free Energy Principle and the Meaning of Life" (MIT Press, 2025)
    Apr 10 2026
    The cybernetic tradition in cognitive science analyzes the purposive behavior of many complex systems – from sensory-guided missiles to sensory-guided animals -- in terms of feedback control that maintains stability in the face of external perturbation. A more recent extension and elaboration of this framework brings in predictive processing and the minimization of free energy – essentially, minimizing getting inputs that conflict with what the system expects. In A Drive to Survive: the Free Energy Principle and the Meaning of Life (MIT Press, 2025), Kathryn Nave argues that this framework is inadequate for explaining living organisms, which are not merely complex but inherently unstable and continually producing themselves through metabolism. Nave, who is a Leverhulme Trust Early Career Research Fellow at the University of Edinburgh, defends a bioenactivist view of living organisms in which the chemical and energetic constraints involved in having a metabolism are essential for understanding their actions, in contrast to the “sensor-guided movementism” of the FEP framework. Learn more about your ad choices. Visit megaphone.fm/adchoices
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    56 mins
  • Douglas H. Erwin, "The Origins of the New: Novelty and Innovation in the History of Life, Culture, and Technology" (Princeton UP, 2026)

    Douglas H. Erwin, "The Origins of the New: Novelty and Innovation in the History of Life, Culture, and Technology" (Princeton UP, 2026)
    Apr 6 2026
    The Origins of the New (Princeton University Press, 2026) presents a revolutionary approach to evolutionary success in all realms of life. In this groundbreaking book, Douglas Erwin takes readers on a dazzling excursion across science and history to explore how evolution generates new and enduring features in biology, culture, and technology.Erwin begins by tracing how thinkers from Darwin’s time to the present day have sought to discover the driving mechanisms of evolutionary novelty. He then lays out compelling empirical evidence for separating novelty from innovation, showing that novelty involves the emergence of unique characteristics, while innovation concerns the success of those characteristics over time. Erwin develops a unifying conceptual framework for these powerful dynamics, demonstrating how they have shaped everything from the evolution of avian feathers and flight to the creation of human language and the breathtaking advances in digital computing we’re witnessing today.A landmark work that redefines our understanding of the changes happening all around us, The Origins of the New reveals how the forces of novelty and innovation are the same across nature and culture, continually producing new forms and refashioning the world as we know it. Our guest is doctor Doug Erwin, who is an independent researcher at the Santa Fe Institute, after retiring as Senior Scientist and Curator of Paleobiology at the National Museum of Natural History of the Smithsonian Institution. Our host is Eleonora Mattiacci, an Associate Professor of Political Science at Amherst College. She is the author of "Volatile States in International Politics" (Oxford University Press, 2023). Learn more about your ad choices. Visit megaphone.fm/adchoices
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    48 mins
  • The Vet at the End of the Earth: Adventures with Animals in the South Atlantic

    The Vet at the End of the Earth: Adventures with Animals in the South Atlantic
    Mar 5 2026
    The role of a resident vet in the remote islands of the Falklands, St. Helena, Ascension, and Tristan da Cunha encompasses many wonderful complexities: caring for the world’s oldest living land animal (a 200-year-old giant tortoise, denizen of the St. Helena governor’s lawn); pursuing mystery creatures and invasive microorganisms; relocating herds of reindeer; and rescuing animals in extraordinarily rugged landscapes, from subtropical cloud forests to volcanic cliff faces. Dr. Hollins’s tales of island vet life are not only full of ingenuity and astounding fauna—they are also steeped in the unique local cultures, history, and peoples of the islands, far from the hustle of continental life. Our guest is: Dr. Jonathan Hollins, who graduated from Emmanuel College, Cambridge, and has been a working vet for four decades. Since the mid-2000s, he has spent long periods as a senior vet overseas in the South Atlantic. He has written for the British national press and presented documentary features for BBC Radio 3 and Radio 4. He lives on St. Helena. Our host is: Dr. Christina Gessler, who is an academic writing coach and editor. She is the producer and show host of the Academic Life podcast. Playlist for listeners: Doctors By Nature Just Like Family Living Night The Killer Whale Journals The Shark Scientist Endless Forms The Well-Gardened Mind Bugs: A Day in the Life My What-if Year The Climate Change Scientist At Every Depth Welcome to Academic Life, the podcast for your academic journey—and beyond! Please join us again to learn from more experts inside and outside the academy, and around the world. Missed any of the 300+ Academic Life episodes? Find them here. And thank you for listening! Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr
  • Robert Endres, "The Unreasonable Likelihood of Being: Origin of Life, Terraforming, and AI" (arXiv, 2025)

    Robert Endres, "The Unreasonable Likelihood of Being: Origin of Life, Terraforming, and AI" (arXiv, 2025)
    Feb 24 2026
    In this episode we discuss the paper "The Unreasonable Likelihood of Being: Origin of Life, Terraforming, and AI" (arXiv, 2025) with Robert Endres. Paper Abstract: The origin of life on Earth via the spontaneous emergence of a protocell prior to Darwinian evolution remains a fundamental open question in physics and chemistry. Here, we develop a conceptual framework based on information theory and algorithmic complexity. Using estimates grounded in modern computational models, we evaluate the difficulty of assembling structured biological in-formation under plausible prebiotic conditions. Our results highlight the formidable entropic and informational barriers to forming a viable protocell within the available window of Earth’s early history. While the idea of Earth being terraformed by advanced extraterrestrials might violate Occam’s razor from within mainstream science, directed panspermia—originally proposed by Francis Crick and Leslie Orgel—remains a speculative but logically open alternative. Ultimately, uncovering physical principles for life’s spontaneous emergence remains a grand challenge for biological physics. Full paper available here Learn more about your ad choices. Visit megaphone.fm/adchoices
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    52 mins
  • Ellen Clarke, "The Units of Life: Kinds of Individual in Biology" (Oxford UP, 2025)

    Ellen Clarke, "The Units of Life: Kinds of Individual in Biology" (Oxford UP, 2025)
    Feb 10 2026
    While we tend to think of biological individuals in terms of paradigmic cases – a dog, a starfish, a bacterium – our ordinary criteria for distinguishing one individual from another are inadequate for making these distinctions in general. If a starfish can literally split itself in two and each half regenerates into a new starfish, why hold that there was just one starfish to begin with rather than many? In The Units of Life: Kinds of Individual in Biology (Oxford UP, 2025), Ellen Clarke defends the idea of evolutionary individuals: units created and maintained by mechanisms that ensure the parts share a common fate. Such individuals enable good evolutionary bookkeeping, in particular our ability to predict which variations in these individuals will enable natural selection to occur. Clarke, an associate professor of philosophy at the University of Leeds, considers the merits of her view in relation to alternatives, how her view explains the emergence of new levels of biological individuality, and how the need for idealization and scientific choice of individual boundaries can avoid conventionalism about biological individuals. Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr and 9 mins
  • Daniel R. Langton, "Darwin in the Jewish Imagination: Jews' Engagement with Evolutionary Theory" (Oxford UP, 2026)

    Daniel R. Langton, "Darwin in the Jewish Imagination: Jews' Engagement with Evolutionary Theory" (Oxford UP, 2026)
    Feb 10 2026
    In this episode, Rabbi Marc Katz sits down with Professor Daniel Langton, author of Darwin in the Jewish Imagination: Jews' Engagement with Evolutionary Theory (Oxford UP, 2026), to explore how Jewish thinkers responded to one of the most disruptive ideas of the modern world: evolutionary theory. Spanning a century of debate, the conversation traces how traditionalists, reformers, secular intellectuals, mystics, and philosophers reimagined Judaism in light of Darwin—from Europe to the United States. Rather than a simple science-versus-religion clash, Langton reveals a rich and creative dialogue shaped by modernity, Jewish-Christian relations, and a distinctive Jewish tendency toward pan(en)theistic thinking—understanding God as deeply intertwined with an evolving universe. Together, Katz and Langton explore how Darwin forced Jewish thinkers to rethink creation, divine action, and morality, and how those debates continue to shape modern Jewish belief and identity. Daniel Langton is Professor of Jewish Studies at the University of Manchester and a leading scholar of modern Jewish thought and Jewish-Christian relations. His work focuses on how Jews have engaged major intellectual movements of modernity, including science, philosophy, and theology. Rabbi Marc Katz is a congregational rabbi, author, and teacher whose work bridges classical Jewish texts and contemporary cultural questions. He is the author of Yochanan’s Gamble: Judaism’s Pragmatic Approach to Life and writes widely on Judaism, ethics, and modern life. Learn more about your ad choices. Visit megaphone.fm/adchoices
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    54 mins