This release contains only the music track from Base by Base Episode 328.

Song title: More Than the Lead
Original Base by Base episode: 328: Variant selection boosts R2 for haptoglobin (HP) in cis‑Mendelian randomization
Original episode link: https://basebybase.com/episodes/hp-variant-selection-cis-mr

Article metadata:
Article title: Variant selection to maximize variance explained in cis-Mendelian randomization
Journal: Human Genetics and Genomics Advances
DOI: 10.1016/j.xhgg.2026.100573
Reference: Zhou A, Karhunen V, Tian H, Pott J, Patel A, Slob EAW, Burgess S. Variant selection to maximize variance explained in cis-Mendelian randomization. Human Genetics and Genomics Advances. 2026 Apr 9;7:100573. https://doi.org/10.1016/j.xhgg.2026.100573.

Lyrics:
Verse 1
Late-night numbers on a bright-screen glow,
One loud signal doesn’t tell you what you know.
In the shadow of the strongest, others hide,
Side by side in patterns, braided in the tide.

Pre-Chorus
Don’t cut the chorus down to one clear tone,
There’s strength in the harmony you’ve never known.
Hold the links steady, let the math stay true,
Pull the quiet threads that tighten up the view.

Chorus
More than the lead, more than a single light,
We take the whole skyline and sharpen the sight.
Higher power, tighter lines, less doubt to read,
When we listen to the neighbors—more than the lead.

Verse 2
Prune it smarter, condition what remains,
Separate the voices running through the veins.
Single-effects, a clean set on the page,
Or let components turn the network into stage.

Bridge
Still we double-check the mirrors for a bend,
Side roads can trick you, drift you from the end.
If the matrix wobbles, slow it down, reset—
Keep the simple answer close, compare the net.

Final Chorus
More than the lead, more than a single light,
We take the whole skyline and sharpen the sight.
Stronger instruments, smaller error, truer read,
With the signals working with us—more than the lead.