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Into the Impossible With Brian Keating

Into the Impossible With Brian Keating

By: Big Bang Productions Inc.
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 Think like a physicist. Wonder like a human. Into the Impossible is where Cosmic Conversations happen — uniting Nobel Prize winners, iconoclasts, authors, and technologists to explore reality’s deepest questions. From AI to aliens, from biophysics to the brain, from the cosmos to the multiverse, Brian Keating, Chancellor’s Distinguished Professor of Physics at UC San Diego covers it all. If you’ve ever asked What’s out there? or What’s next?, this is where curiosity meets clarity. Learn to think like this. 🎙 Full episodes, notes & more: briankeating.com/podcast© 2025 Big Bang Productions Inc. 719843 Nature & Ecology Physics Science
Episodes
  • What's The Real Value of Your Degree? Aswath Damodaran

    What's The Real Value of Your Degree? Aswath Damodaran
    Mar 9 2026
    Please join my mailing list here 👉 https://briankeating.com/list to win a meteorite 💥 Aswath Damodaran joins Brian Keating to argue that markets, universities, and financial models are all suffering the same disease — mistaking mechanical processes for genuine thinking — and explains why Nobel economists aren't billionaires, why academia is the most deserving target for disruption, and why every major asset class is now overpriced with nowhere left to hide. 00:00 Intro 00:01:37 Why Nobel Economists Aren't Billionaires 00:06:08 Universities Have Completely Lost the Plot 00:07:43 95% of Academic Research Is Worthless 00:13:05 The University Is a Sticky Business — But Cracks Are Forming 00:40:00 ChatGPT Already Does What Bankers Charge Millions For 00:46:43 The Most Dangerous Number in Finance 00:52:35 There Is No Safe Place Left to Put Your Money 00:55:48 When Every Asset Is Overpriced, Buy What You Love 01:00:22 We Are Losing Our Ability to Think 01:01:30 Markets Are Smarter Than Experts — Every Single Time ➡️ Follow Aswath Damodaran 🌐 Website: https://pages.stern.nyu.edu/~adamodar/ 📚 The Little Book of Valuation: https://pages.stern.nyu.edu/~adamodar/ 📝 Musings on Markets (Substack): https://aswathdamodaran.substack.com Join this channel to get access to perks like monthly Office Hours: https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join 📚 Get my books: Think Like a Nobel Prize Winner, with productivity tips from 9 Nobel Prize winners: https://a.co/d/03ezQFu Focus Like a Nobel Prize Winner, with life-changing interviews with 9 Nobel Prizewinners: https://a.co/d/hi50U9U My tell-all cosmic memoir Losing the Nobel Prize: http://amzn.to/2sa5UpA The first-ever audiobook from Galileo: Dialogue Concerning the Two Chief World Systems: Ptolemaic and Copernican https://a.co/d/iZPi9Un Follow me to ask questions of my guests: 🏄‍♂️ Twitter: https://twitter.com/DrBrianKeating 🔔 Subscribe https://www.youtube.com/DrBrianKeating?sub_confirmation=1 📝 Join my mailing list; just click here http://briankeating.com/list ✍️ Detailed Blog posts here: https://briankeating.com/blog 🎙️ Listen on audio-only platforms: https://briankeating.com/podcast #universe #podcast #briankeating #intotheimpossible #science #astronomy #cosmology #cosmicmicrowavebackground #intotheimpossible #briankeating Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr and 12 mins
  • Will AI Replace Scientists?

    Will AI Replace Scientists?
    Mar 6 2026
    Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 In this video, we discuss the rapidly evolving intersection of artificial intelligence and fundamental science and how AI is transforming the way physicists handle massive streams of data from modern observatories—while also explaining where its power ends and human creativity begins. Tune in for insights, surprising stories, and a behind-the-scenes look at how scientists are navigating the AI revolution. 🚀 - Key Takeaways: 00:00 - Cosmologist Exploring Universe and AI 05:30 - AI Success and Physics Limits 09:48 - How Did the Universe Begin? 14:00 - Limits of AI in Scientific Insight 16:04 - Cosmology's Data Revolution 19:29 - AI Insights: Science and Writing 23:04 - Limits of Predictive Models 25:32 - AI's Academic Impact: Pros & Cons 33:24 - LLM Chips and AI Accuracy 34:41 - Accountability, Writing, and Discovery - Join this channel to get access to perks like monthly Office Hours: https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join 📚 Get my books: Think Like a Nobel Prize Winner, with productivity tips from 9 Nobel Prize winners: https://a.co/d/03ezQFu Focus Like a Nobel Prize Winner, with life-changing interviews with 9 Nobel Prizewinners: https://a.co/d/hi50U9U My tell-all cosmic memoir Losing the Nobel Prize: http://amzn.to/2sa5UpA The first-ever audiobook from Galileo: Dialogue Concerning the Two Chief World Systems: Ptolemaic and Copernican https://a.co/d/iZPi9Un Follow me to ask questions of my guests: 🏄‍♂️ Twitter: https://twitter.com/DrBrianKeating 🔔 Subscribe https://www.youtube.com/DrBrianKeating?sub_confirmation=1 📝 Join my mailing list; just click here http://briankeating.com/list ✍️ Detailed Blog posts here: https://briankeating.com/blog 🎙️ Listen on audio-only platforms: https://briankeating.com/podcast #universe #podcast #briankeating #intotheimpossible #science #astronomy #cosmology #cosmicmicrowavebackground #artificialintelligence #aiinscience #physics #machinelearning #futureofscience #aiandscience #scienceexplained #aiuniverse Learn more about your ad choices. Visit megaphone.fm/adchoices
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    41 mins
  • Nick Lane: The Engine That Built Life

    Nick Lane: The Engine That Built Life
    Mar 3 2026
    Please join my mailing list here 👉 https://briankeating.com/yt to win a meteorite 💥 Nick Lane joins Brian Keating to argue that life is not information running on chemistry but energy in motion—showing how a single ancient metabolic “transformer” predates genes, powers mitochondria, shapes aging and cancer, constrains alien life, and reveals why today’s AI excitement echoes a solution biology discovered billions of years ago. 00:00 — Defining life vs. death; membrane potential as the boundary between living and dead 00:50 — The title “Transformer” and parallels between AI transformers and biochemical transformation 03:22 — Schrödinger’s What Is Life? and why defining life is intrinsically slippery 06:25 — Why the Krebs cycle sits at the center of metabolism 08:45 — The reverse Krebs cycle, CO₂ fixation, and links to cancer metabolism 11:35 — Mitochondrial membrane potential and the electrical field that powers life 15:00 — Reverse Krebs cycle vs. Calvin cycle and the evolution of carbon fixation 18:00 — Endosymbiosis: origin of mitochondria and chloroplasts 30:02 — Metabolism before genes; CO₂ + hydrogen and prebiotic chemistry 59:49 — Rapid-fire Q&A: RNA world critique and big open questions in origin-of-life research ------------------------------------------------------ ➡️ Follow Nick Lane 🌐 Website: https://www.nick-lane.net 📚 Transformer: The Deep Chemistry of Life and Death: https://nick-lane.net/books/transformer-the-deep-chemistry-of-life-and-death/ Join this channel to get access to perks like monthly Office Hours: https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join 📚 Get my books: Think Like a Nobel Prize Winner, with productivity tips from 9 Nobel Prize winners: https://a.co/d/03ezQFu Focus Like a Nobel Prize Winner, with life-changing interviews with 9 Nobel Prizewinners: https://a.co/d/hi50U9U My tell-all cosmic memoir Losing the Nobel Prize: http://amzn.to/2sa5UpA The first-ever audiobook from Galileo: Dialogue Concerning the Two Chief World Systems: Ptolemaic and Copernican https://a.co/d/iZPi9Un Follow me to ask questions of my guests: 🏄‍♂️ Twitter: https://twitter.com/DrBrianKeating 🔔 Subscribe https://www.youtube.com/DrBrianKeating?sub_confirmation=1 📝 Join my mailing list; just click here http://briankeating.com/list ✍️ Detailed Blog posts here: https://briankeating.com/blog 🎙️ Listen on audio-only platforms: https://briankeating.com/podcast #universe #podcast #briankeating #intotheimpossible #science #astronomy #cosmology #cosmicmicrowavebackground #intotheimpossible #briankeating Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr and 15 mins
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