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The Groysman Podcast

The Groysman Podcast

By: Robert Groysman M.D.
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About this listen

The Groysman Podcast decodes chronic illness with evidence-based insights from Dr. Robert Groysman, a board-certified physician specializing in complex chronic conditions, like ME/ CFS.

Whether you're dealing with Long COVID, POTS, chronic fatigue, mast cell activation, or any condition affecting multiple body systems, Dr. Groysman explains what's happening beneath the surface. Drawing from over five years treating thousands patients and his personal experience with chronic illness, he translates cutting-edge research into practical insights you can use.

Episodes cover root mechanisms, from dysautonomia and mitochondrial dysfunction to gut dysbiosis and hormone imbalance, and the advanced treatments addressing them. You'll learn why symptoms persist, what triggers make them worse, and which evidence-based strategies may support your recovery journey.

Dr. Groysman brings a unique perspective as both treating physician and someone who's personally navigated Long COVID.

As founder of the COVID Institute and author of The Complete Long COVID Handbook series, Dr. Groysman has developed systematic frameworks for addressing chronic conditions. But this isn't about protocols—it's about understanding your body, connecting the dots between symptoms, and finding your path forward.

New episodes weekly.

Copyright 2026 All rights reserved.
Episodes
  • Long COVID brain fog explained: The biological mechanisms behind the symptoms

    Long COVID brain fog explained: The biological mechanisms behind the symptoms
    Feb 24 2026

    In this episode, Dr. Robert Groysman breaks down why brain fog in Long COVID is not psychological, it is a measurable biological problem with multiple distinct causes. He covers dysautonomia's effect on cerebral blood flow, mitochondrial dysfunction and why the brain is uniquely vulnerable to energy deficits, neuroinflammation from overactive microglia, endothelial dysfunction and microclots impairing oxygen delivery, hormone disruption across thyroid, adrenal, and sex hormone systems, sleep architecture loss, gut-brain axis dysregulation through the vagus nerve, and post-exertional cognitive crashes.

    What You'll Learn:

    • Why the brain uses 20% of your body's total energy and what happens when ATP production drops
    • How dysautonomia causes cerebral blood flow to fluctuate with posture, activity, and even eating
    • Why your MRI can look completely normal while neuroinflammation is still actively impairing cognition
    • How the gut communicates with the brain through the vagus nerve, and why gut dysbiosis worsens mental clarity
    • The post-exertional pattern: why cognitive crashes can appear hours after the triggering activity
    • Why identifying which specific mechanism is driving your brain fog is the key to addressing it

    ---

    The Complete Long COVID Handbook Series (7 volumes) - Comprehensive guides covering 100+ symptoms, mechanisms, and evidence-based approaches across all six primary causal mechanisms. → https://www.longcovidfamily.com/shop/

    Join the Long COVID Family Community - Connect with other Long COVID patients, access free resources, and stay updated on the latest research. → https://www.longcovidfamily.com/
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    5 mins
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