Huberman Lab cover art

Huberman Lab

Huberman Lab

By: Scicomm Media
Listen for free

About this listen

 The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works. Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017. Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.Copyright © 2021-2025 Scicomm Media LLC Biological Sciences Hygiene & Healthy Living Science
Episodes
  • Male vs. Female Brain Differences & How They Arise From Genes & Hormones | Dr. Nirao Shah

    Male vs. Female Brain Differences & How They Arise From Genes & Hormones | Dr. Nirao Shah
    Jul 28 2025
    My guest is Dr. Nirao Shah, MD, PhD, a professor of psychiatry, behavioral sciences and neurobiology at Stanford University School of Medicine. We discuss how the brains of males and females differ and how those differences arise from different genes and hormones during fetal development, in childhood and adulthood. We discuss what drives male- versus female-specific behaviors and how hormonal fluctuations across the lifespan, including puberty, the menstrual cycle, menopause and aging – affect behavior, cognition and health. Additionally, we discuss how biology relates to gender identity and the impact of hormone therapies on brain circuits that regulate mating, parenting and social bonding. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui: https://mauinuivenison.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Nirao Shah 00:02:11 Mice, Humans & Brain, Biological Conservation 00:05:25 Hormones, Nature vs Nurture 00:07:13 Biological Sex Differences, Chromosomes & SRY Gene, Hormones 00:16:01 Sponsors: Maui Nui & Eight Sleep 00:19:09 Androgen Mutations, Feminization & Masculinization 00:22:04 SRY Gene; Animals & Sexual Trans-Differentiation 00:27:49 Hormones & Biological Brain Differentiation 00:31:22 Congenital Adrenal Hyperplasia, Androstenedione; Stress & Pregnancy 00:35:56 Genes, Brain Differentiation & Sexual Identity; Congenital Adrenal Hyperplasia 00:43:37 Testosterone, Estrogen & Brain Circuits 00:47:27 Sponsors: AG1 & LMNT 00:50:36 Intersex Individuals, Castration 00:52:23 Female Sexual Behavior, Brain, Testosterone & Pheromones 00:57:58 Identify as Heterosexual or Homosexual, Difference in Hormone Levels? 01:00:42 Gender, Sexual Orientation & Hormones; Hormone Replacement Therapy 01:10:21 Aromatization; Steroid Hormones & Gene Expression 01:15:00 Kids & Changing Gender Identity 01:19:05 Sexual Behavior, Refractory Period & Male Brain, Tacr1 Cells 01:21:31 Sponsor: Function 01:23:19 Hypothalamus, Dopamine, Prolactin, Cabergoline, Libido, Dopamine 01:27:05 Brain Circuits, Aggression & Sexual Behavior 01:32:40 Refractory Period; Age, Testosterone & Libido 01:36:07 Tacr1 Cells in Females, Periaqueductal Gray & Innate Behaviors 01:40:00 Parenting Behaviors & Brain Circuits; Pet Dogs 01:43:12 Oxytocin, Pair Bonding, Vasopressin; Biological Redundancy 01:47:22 Libido, Melanocortin, Tacr1 Neurons; GLP-1 Agonists, Clinical Trials; Kisspeptin 01:56:43 Female Brain Changes, Menstrual Cycle, Pregnancy, Menopause; Estrogen; Men & Hormone Fluctuation? 02:04:10 Life Experience Male vs Female, Sex Recognition, Behaviors & Context 02:16:05 Pain Management; Endocrine Disrupters, Gender Identity 02:21:03 Future Projects 02:24:29 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
    Show More Show Less
    2 hrs and 27 mins
  • Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson

    Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson
    Jul 24 2025
    In this Huberman Lab Essentials episode, my guest is Dr. Matthew Johnson, PhD, a senior researcher for the Center of Excellence for Psilocybin Research and Treatment at Sheppard Pratt’s Institute for Advanced Diagnostics and Therapeutics. We explore the science and therapeutic potential of psychedelic medicine, including psilocybin, MDMA and LSD. We discuss how these substances can profoundly alter perception and self-identity, providing long-lasting relief from depression, addiction and trauma when used in controlled clinical settings. We also discuss microdosing and emerging research on psychedelics’ potential to support recovery from neurological injuries. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman BetterHelp: https://betterhelp.com/huberman Timestamps 00:00:00 Matthew Johnson; Psychedelics 00:01:44 Different Classes of Psychedelics 00:04:33 Psychedelics & Altering Models 00:06:18 Sponsor: David 00:07:33 LSD, Psylocibin & Serotonin 00:09:55 Psychedelic Clinical Trials 00:13:40 Therapy, Trust, Psychedelics 00:16:47 Letting Go & Psychedelic Experience, Self-Representation, Lasting Changes 00:22:31 Sponsors: AG1 & BetterHelp 00:25:26 MDMA, Dopamine & Serotonin; Bad Trips & Transcendental Experience 00:28:49 Dangers of Psychedelics 00:31:11 Microdosing Psychedelics, Antidepressant 00:35:27 Head Injuries, Psychedelics, Depression 00:38:29 Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
    Show More Show Less
    39 mins
  • Health Effects & Risks of Kratom, Opioids & Other Natural Occurring Medicines | Dr. Chris McCurdy

    Health Effects & Risks of Kratom, Opioids & Other Natural Occurring Medicines | Dr. Chris McCurdy
    Jul 21 2025
    My guest is Dr. Chris McCurdy, PhD, FAAPS, professor of medicinal chemistry at the University of Florida and a world expert on the pharmacology of kratom and other plant-derived medicinal compounds. We discuss kratom’s wide-ranging effects, including its use for boosting energy, enhancing mood, managing pain and as a potential opioid substitute, while also explaining its critical safety concerns and addictive potential, especially for kratom-derived/isolate products. We also discuss plant-based compounds more generally for their potential benefits and risks. Dr. McCurdy offers a balanced perspective on kratom and other plant-based and naturally occurring medicinal compounds, highlighting and contrasting their promise for human health with potential serious risks. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David Protein: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Chris McCurdy 00:02:51 Kratom (Mitragyna speciosa), Origin, Effects, Low vs High Doses 00:07:19 Sponsors: David Protein & Eight Sleep 00:10:07 Kratom, Traditional Use vs Commercial Kratom Products, Absorption 00:17:00 Kratom Products, Serving Size, Kids; Semi-Synthetics; Tool: Understand Kratom Product Labels 00:23:16 Kratom Products & Various Desired Effects; Physical Dependence 00:32:53 Different Kratom Usage Patterns, Opioid Dependence 00:36:59 Alkaloid Compounds, Nitrogen, Nicotine; Animals & Self-Experimentation 00:47:47 Sponsors: AG1 & ROKA 00:51:05 Medicine Development, Disconnection from Nature, Product Concentrations 00:59:00 Alkaloids & Natural Products, Opium Poppy, Coca Leaf, Tool: Kratom Leaf vs Extracts (Kratom-Derived/Kratom Isolates) 01:09:06 Is It Safe for Kids to Consume Kratom Products? 01:12:19 Kratom, Energy, Mood & Pain Management, Dose; Caffeine 01:16:56 Respiratory Depression & Kratom Products 01:20:16 Sponsor: Function 01:22:04 Kratom Leaf vs Derivatives, FDA Regulations, Usage Guidelines 01:26:59 Kratom, Alcohol Consumption, Respiratory Failure? 01:29:09 Kratom Alkaloids, Mood & Stimulant Effects, Multiple Pathways for Pain Relief 01:38:17 Plant Alkaloids & Chemical Defense, Kratom & Antifungal Alkaloids; Geckos 01:44:35 White, Red & Brown Vein Kratom, Leaf Processing; Terpenes 01:51:08 Kratom as an Anti-Depressant?; Discontinuing Kratom Use, Opioid Use 01:58:03 Kratom, Drug Interactions & Seizure, Opioids 02:01:51 Cacao Beans, Chocolate 02:09:34 Coca-Cola, Coca Plant & Cocaine, History of Soft Drinks 02:19:49 Career Journey, Pharmacy, Chemistry & Education, Lobelia 02:28:44 Nicotine; Natural Products & Career Journey, Salvia divinorum, Kratom 02:40:22 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
    Show More Show Less
    2 hrs and 44 mins

What listeners say about Huberman Lab

Average Customer Ratings
Overall
  • 4.5 out of 5 stars
  • 5 Stars
    21
  • 4 Stars
    0
  • 3 Stars
    0
  • 2 Stars
    2
  • 1 Stars
    0
Performance
  • 4.5 out of 5 stars
  • 5 Stars
    21
  • 4 Stars
    0
  • 3 Stars
    0
  • 2 Stars
    2
  • 1 Stars
    0
Story
  • 4.5 out of 5 stars
  • 5 Stars
    21
  • 4 Stars
    0
  • 3 Stars
    0
  • 2 Stars
    0
  • 1 Stars
    2

Reviews - Please select the tabs below to change the source of reviews.

Audible.com.au reviews

Amazon Reviews
Sort by:
Filter by:
  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for Gillian Read

I love this stuff!!!

I love all things science-y about us humans.
This podcast is on par with David Sinclair’s.
Love this podcast.

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for Kat

Delightful mix of deep science and everyday wisdom

Andrew, thank you for what you do. I've been listening to the Huberman Lab podcast on Audible for over a year now, and it's been an absolutely delightful journey. The topics always surprise me with how relevant they feel to my life. I love his sense of humour and how he conducts interviews.

I've improved my daily routines, workouts, and supplements thanks to the actionable insights he shares. His ability to connect science to everyday choices is truly powerful.

I genuinely hope you visit Australia again soon—your audience here would love to see you!

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for Anonymous User

Best podcasts I've ever listened to

Love these, such great bite size chunks you can give a go in your own time and every time I have found an improvement 👍
I love that it's science based and provides the explanations instead of "just do this"
10/10

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for Anonymous User

Well Spoken, expert subject knowledge

Very research based arguments with examples and ways to apply to yourself and thus benefit your actual life. Lots to learn that is spoken in a very active way, I would highly recommend to anyone looking to optimise their life, learn more about the brain or the best ways to learn.

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for Anonymous User

Highly useful information that I fully utilise.

it's a wonderful contribution .
I follow all the beautifully information daily.
I thank the good Dr☯️✌👍

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for ameal

great content, protocol and science based.

Definitely a need to have podcast for self care, obviously we are all different so it's depending and needs to be adjusted to who you are or you can actually live your life and whine less give it everything you got regardless if it's painful, the reward is too great to be like everyone else.

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for Amazon Customer

Brain science made accessible with loads of hacks

I love this man and his work, everyone should listen to understand the biology behind our behaviours, thoughts, experiences and reactions. He makes neurology accessible and shares the latest research and learnings on how we can hack our brains to get the outcomes we desire. Covering a vast array of subjects there is something for everyone.

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for Dan

Probably the most positive and concise content.

I can’t rate this highly enough. This has changed my entire view. Cutting through all the conflicting information and giving definitive information that can be applied by anyone.

Thank you Huberman Lab.

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

  • Overall
    5 out of 5 stars
  • Performance
    5 out of 5 stars
  • Story
    5 out of 5 stars
Profile Image for Anonymous User

knowledge is power

fantastic insight into the human body on multiple facets learning tools and methods which you can applybto everyday life.

Report this

Something went wrong. Please try again in a few minutes.

You voted on this review!

You reported this review!

In the spirit of reconciliation, Audible acknowledges the Traditional Custodians of country throughout Australia and their connections to land, sea and community. We pay our respect to their elders past and present and extend that respect to all Aboriginal and Torres Strait Islander peoples today.