How a Short-Lived Fish Teaches Us About Aging
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How a Short-Lived Fish Teaches Us About Aging
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About this listen
In this episode of Biology Career Insights, we dive into groundbreaking research using the African turquoise killifish, a fast-aging vertebrate, to study kidney aging. Despite their naturally short lifespan, these tiny fish are helping scientists uncover how SGLT2 inhibitors—drugs originally developed for diabetes—can preserve kidney function, protect capillary networks, and prevent inflammatory damage as organs age.We explore why these medications provide cardiovascular and renal benefits in humans far beyond blood sugar control and how studying rapid-aging species accelerates the development of life-extending therapies.🎙️ Powered by AI, curated by scientists, and made for educational purposes only.🔔 Don’t forget to subscribe for more insights into biology careers, cutting-edge research, and the stories shaping the future of biotechnology.Timestamps (Optional):0:00 – Introduction1:20 – Why the African turquoise killifish is a unique aging model3:45 – SGLT2 inhibitors and kidney preservation6:30 – Implications for human health and longevity9:00 – Key takeaways