Dante answers a listener question about how prebiotics, fiber supplements, and whether they interact with Lipitor. There's a lot of hype around prebiotics, but is any of it justified?

Plus, a new study illustrates the opposing roles dopamine and serotonin play in shaping our decisions and learning processes. Joey discusses how understanding these key brain chemicals can lead to faster learning and avoiding the same spiral of chasing dopamine with things like social media doom scrolling.

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Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:28 - Show Intro
01:25 - Listener Question: Prebiotics
02:05 - What are Prebiotics?
04:03 - Good vs. Bad Gut Bacteria
09:20 - What are naturally occurring prebiotics?
13:59 - Can prebiotics curb appetite?
17:09 - Will prebiotics interfere with statins?
20:20 - What is the pre/pro/postbiotic process?
22:11 - Why do we care about postbiotics?
26:35 - Prebiotic Soda
28:44 - Serotonin and Dopamine
30:17 - What are Dopamine and Serotonin?
32:41 - Synergy Hypothesis & Opponency Hypothesis
33:39 - Study Findings
41:41 - Connection with depression and addiction
46:25 - Show Outro

SHOW NOTES:
1) Dopamine and serotonin's opposing roles (PsyPost) - https://tinyurl.com/52sbb8a2
2) Dopamine and Serotonin (Study) - https://www.nature.com/articles/s41586-024-08412-x

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

President Trump, now in his second term, has signed two executive orders he believes will lower prescription drug prices. He's pressuring "big pharma", trying to cut out PBM's (Pharmacy Benefits Managers), and restricting how much Medicare and Medicaid will pay. Is it enough? Are these even the right targets? What will all of this mean when picking up a prescription? We dig into the details and take a look at what all of this means for your wallet.

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CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowYTM
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
01:16 - Executive Orders Overview
03:21 - Most Favored Nation
05:50 - How did we get here?
06:25 - Price Controls
08:10 - Patent Laws & Exclusivities
10:51 - What are PBMs?
12:55 - Big 3 PBMs
21:53 - Direct to Consumer Rx
23:44 - Medicare Price Negotiations
31:58 - Show Outro

SHOW NOTES:
1) Prescription Drug Pricing (White House) - https://tinyurl.com/2bcj6dbt
2) Plan to pressure drug companies to lower costs (ABC News) - https://tinyurl.com/5x98wp6n
3) Lowering Drug Prices (White House) - https://tinyurl.com/3cak5y5m
4) Fact Sheet: Lower Prescription Drug Prices (White House) - https://tinyurl.com/4bchne2v
5) Letter to Drug Manufacturers (X) - https://tinyurl.com/4hcc7rna

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

When two different studies came out looking at the association of type 2 diabetes and Alzheimer's risk, we knew we had to dig in! What exactly are the risks? What is the connection? Do any medicines help negate those risks? Joey has the details.

What's in the Bottle? Creatine Essentials! Creatine has been getting a ton of press lately, and for good reason! While the body makes a limited amount of creatine on its own, nearly everyone can benefit from supplementing with it. It improves athletic performance by allowing muscles to work harder for just a bit longer. What's more, several recent studies are showing that it helps the brain by reducing the worst effects of poor sleep.

ALL PRODUCTS: https://www.AskJoeDimatteo.com

CONNECT:
Products - https://askjoedimatteo.com/youtube
Questions - questions@askjoedimatteo.com
Facebook - https://facebook.com/askjoedimatteo
Instagram - https://tinyurl.com/5n6kfwhs

PODCAST:
Apple Podcasts - https://tinyurl.com/GHShowApple
Google Podcasts - https://tinyurl.com/GHShowGoogle
Spotify - https://tinyurl.com/GHShowSpotify
Rumble - https://rumble.com/user/GenerationHealth
YouTube - https://tinyurl.com/57hxe6aj
YouTube Clips - https://tinyurl.com/wzk69tbk

Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

CHAPTERS:
00:32 - Study: Type 2 Diabetes & Alzheimer’s
02:55 - Study Summary
07:42 - Study: Diabetes Meds & ALZ Risk
09:41 - Study Summary
11:09 - GLP-1 and SGLT-2 impact on dementia
14:35 - Obesity & Alzheimer’s
16:58 - What’s in the Bottle: Creatine Essentials
17:47 - What is Creatine?
20:02 - Who is creatine supplementation for?
25:01 - Are there risks?
28:20 - How do you use Creatine Essentials?
30:31 - Show Outro

SHOW NOTES:
1) Type 2 Diabetes Rewires the Brain (NeuroscienceNews) - https://tinyurl.com/4skhvcs5
2) Diabetes Rewires the Brain (Pharmacy Times) - https://tinyurl.com/yszyksey
3) Diabetes drugs may slash Alzheimer's risk (MedicalNewsToday) - https://tinyurl.com/tjmxmrmy
4) GLP-1, Parkinson’s Disease (The New England Journal of Medicine) - https://tinyurl.com/465njwjv
5) Treatment for people with Parkinson's disease (Lancelet) - https://tinyurl.com/yjunh4s6
6) BCAAs on Muscle During Exercise (NIH) - https://tinyurl.com/2dpbz9vu
7) Whey protein as a source of peptides (Research Gate) - https://tinyurl.com/4wfz937u
8) Protein - Which is Best? (NIH) - https://tinyurl.com/3athvss8
9) Health Benefits of Whey Protein (ResearchGate) - https://tinyurl.com/mry4mvh4
10) Whey protein isolate attenuates strength decline (NIH) - https://tinyurl.com/2d44pa5w
11) Functional properties of whey (NIH) - https://tinyurl.com/mr48wuff
12) Relevance of whey protein (ScienceDirect) - https://tinyurl.com/p7p2uf8n

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.