In this episode of Curing with Sound, we speak with Dr. Jean-François Aubry, Director of Research at France's National Center for Scientific Research and a leading expert in therapeutic ultrasound with over two decades of experience in the field. Dr. Aubry discusses transcranial ultrasound stimulation (TUS), an emerging neuromodulation approach that enables precise targeting of deep brain structures without surgery, opening new avenues for treating some of the most challenging neurological and psychiatric disorders.

He also shares compelling findings from his recent clinical trial evaluating the safety of TUS for drug-resistant depression, in which 80% of patients responded to the treatment, highlighting the potential of ultrasound neuromodulation as a noninvasive therapeutic approach.

Discussion highlights:

• Focused Ultrasound Center of Excellence: Dr. Aubry is the Scientific Director of the Focused Ultrasound Center of Excellence at Physics for Medicine Paris. The laboratory’s mission is to invent innovative technologies for medical imaging and therapy, providing patients and clinicians with ultrasound-based therapies as a noninvasive alternative to surgical procedures.
• Depression Treatment Breakthrough: Dr. Aubry is a co-founder of Sonomind, a company dedicated to tackling drug-resistant depression and other neuropsychiatric disorders. The company’s personalized transcranial neuromodulation system enables noninvasive targeting of deep brain regions with unprecedented precision.

EPISODE TRANSCRIPT

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