Ep 113- "ICU Perspectives: Understanding the Heart-Kidney Link"

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Ep 113- "ICU Perspectives: Understanding the Heart-Kidney Link"

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In this podcast episode, we’ll explore acute cardiorenal syndrome, specifically type 1, where worsening kidney function stems directly from acute heart failure. We’ll unpack the complex pathophysiology of CRS type 1, diving into both hemodynamic factors, like renal venous congestion, and non-hemodynamic factors, such as the activation of the renin-angiotensin-aldosterone system (RAAS) and inflammatory pathways. Next, we’ll discuss the diagnostic tools that help identify CRS type 1, from lab markers and imaging techniques to invasive hemodynamic monitoring. Finally, we’ll cover preventative and treatment strategies, including diuretics, RAAS inhibitors, sodium-glucose cotransporter-2 inhibitors (SGLT-2i), renal replacement therapy, and additional therapies like hypertonic saline, chloride-based treatments, and device-based interventions.

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