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Dr. M's Women and Children First Podcast

Dr. M's Women and Children First Podcast

By: Dr. Chris Magryta "Dr. M"
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 Providing listeners with cutting edge science based information for maternal and child health©Copyright 2021 Krzysz Media LLC Hygiene & Healthy Living Physical Illness & Disease
Episodes
  • Dr. M’s Women and Children First Podcast #107: Sundeep Dugar, PhD – Drug Discovery

    Dr. M’s Women and Children First Podcast #107: Sundeep Dugar, PhD – Drug Discovery
    Mar 2 2026
    On today’s episode of Dr. M’s Women and Children First Podcast, we welcome a scientist whose work has quietly shaped the cardiovascular health of millions around the world. Dr. Sundeep Dugar is a pharmaceutical innovator, inventor, and industry leader with more than three decades at the forefront of drug discovery. He is best known as a co-inventor of ezetimibe — marketed as Zetia® — a landmark cholesterol-lowering medication that transformed lipid management by targeting intestinal cholesterol absorption. He also co-inventor of the combination therapy Vytorin® (ezetimibe plus simvastatin), expanding treatment options for patients at high cardiovascular risk. For this groundbreaking work, Dr. Dugar and his colleagues received the prestigious 2005 National Inventor of the Year Award from the Intellectual Property Owners Association and the Heroes of Chemistry award from the American Chemical Society. Across his career, Dr. Dugar has contributed to more than 140 patents and has authored over 70 scientific publications, reflecting a lifetime devoted to translating chemistry into real-world therapies. He is currently the founder of Aayam Therapeutics, where he leads efforts to develop innovative, accessible medicines through collaborative global research. He also serves as Co-Chief Executive Officer of Blue Oak Nutraceuticals, advancing a novel mitochondrial-targeted compound known as Mitokatlyst™, designed to stimulate mitochondrial biogenesis and cellular energy — with potential implications for muscle strength, metabolic health, cardiovascular function, and inflammation. He is the first one to decipher the mechanism by which exercise induces mitochondria levels. Mitokatlyst mechanism of action mimics this process. Dr. Dugar’s scientific journey spans continents and some of the world’s premier institutions. He earned both his Bachelor’s and Master’s degrees in Organic Chemistry from the University of Delhi, completed his PhD in Chemistry at the University of California, Davis, and pursued postdoctoral research at ETH Zürich in Switzerland and at Cornell University. Today, we’ll explore the story behind major pharmaceutical breakthroughs, the science of mitochondrial health, and what the future of therapeutics may look like when innovation meets global accessibility. Please join me in welcoming Dr. Sundeep Dugar.
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    1 hr and 12 mins
  • Dr. M’s SPA Newsletter Volume 16 Issue 4 – Relationships

    Dr. M’s SPA Newsletter Volume 16 Issue 4 – Relationships
    Feb 20 2026
    Screenshot Literature Review: A) "Establishment of the gut microbiome during early life is a complex process with lasting implications for an individual’s health. Several factors influence microbial assembly; however, breast-feeding is recognized as one of the most influential drivers of gut microbiome composition during infancy, with potential implications for function. Differences in gut microbial communities between breast-fed and formula-fed infants have been consistently observed and are hypothesized to partially mediate the relationships between breast-feeding and decreased risk for numerous communicable and noncommunicable diseases in early life. Despite decades of research on the gut microbiome of breast-fed infants, there are large scientific gaps in understanding how human milk has evolved to support microbial and immune development." (Davis et. al. 2022) Main Takeaways: First 1000 days matter a lot for microbial and immune development: Infancy is a critical window when the gut microbiome is assembled and the immune system is learning to respond to microbes and external exposures. Patterns set early can ripple into infection risk, inflammatory diseases, and atopy later in life. Enjoy, Dr. M
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    12 mins
  • Dr. M’s SPA Newsletter Volume 16 Issue 3 – Beyond Behaviors Chapter 4

    Dr. M’s SPA Newsletter Volume 16 Issue 3 – Beyond Behaviors Chapter 4
    Feb 14 2026
    Chapter 4 of Beyond Behaviors is often read as a continuation of the neuroscience laid out in the first three chapters. That’s understandable, but it slightly misses the point. By the time Dr. Delahooke gets to Chapter 4, she’s largely done making the physiological argument. She now pivots to a far more practical and, frankly, more uncomfortable question: What does this mean we actually do as caregivers? This chapter is less about how the nervous system works and more about how we work, how we observe, interpret, and respond to children in real time. It’s a chapter about attunement, not theory. About shifting from reflexive reactions to intentional caregiving. About learning to read the child in front of you, not the rulebook in your head. The first major move of Chapter 4 is the insistence on personalized attunement, ditching the plural child. Or better yet, focused on the N of 1 child. There is no “average child” in her framework. There is only this child, with this nervous system, in this moment, in this space and time. How beautiful! Integrative Functional Medicine's credo, treat the whole person as you find them and as they are biologically. Attunement here is not sentimentality. It’s data gathering. Dr. Delahooke asks caregivers to become skilled observers of patterns rather than judges of behavior. What time of day does dysregulation tend to show up? After which transitions? After eating? After playing video games? In which environments? With which sensory demands? With which people? It is sleuthing the underwater potion of the iceberg of behavior. Importantly, she pushes caregivers to stop assuming intent. The question is not “Why is my child doing this to me?” but “What is my child’s nervous system experiencing right now?” That single frame shift collapses an enormous amount of unnecessary conflict. It moves the adult from adversary to ally. It walks away from shame and blame towards love and support..... Enjoy, Dr. M
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    15 mins
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