In this special crossover episode, recorded live at the American Diabetes Association’s 85th Scientific Sessions in Chicago, the hosts of ADA’s professional podcasts—Diabetes Core Update, Diabetes Care “On Air”, and DiabetesBio—come together to discuss key highlights and groundbreaking research presented at the 2025 meeting.

They share expert insights across the bench-to-bedside spectrum, including basic science, clinical research, and the latest in diabetes care and education. Tune in for thoughtful reflections on what this year’s findings mean for clinical practice and future research.

Available now across all ADA professional podcast channels.

Featured Podcasts:

• DiabetesBio – From ADA’s flagship research journal, Diabetes

• Diabetes Care “On Air” – From ADA’s clinical research journal, Diabetes Care

• Diabetes Core Update – ADA’s podcast for primary care

Join the Discussion with:

• Alice Cheng, MD – Co-host of Diabetes Care “On Air”

• Kirk Habegger, PhD – Co-host of DiabetesBio

• Michael Rickels, MD, MS – Co-host of Diabetes Care “On Air”

• Darleen Sandoval, PhD – Co-host of DiabetesBio

• Neil Skolnik, MD – Co-host of Diabetes Core Update and Diabetes Day by Day

• Kevin Williams, PhD – Co-host of DiabetesBio

🔗 Learn more about ADA’s full podcast portfolio:
https://diabetesjournals.org/journals/pages/podcasts

Subscribe to Diabetes Core Update, Diabetes Care “On Air”, and DiabetesBio on Apple Podcasts, Amazon Music, Spotify, or your preferred platform.

Welcome to the August 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the August 2025 issue of Diabetes.

6:55 For this month’s episode, a special extended edition of “Sweet Talk,” exploring the debate about whether GIP receptor agonism or GIP receptor antagonism holds the most promise for therapeutic strategies. First, our hosts are joined by Daniel J. Drucker, OC, MD, FRCPC, FRSC, FRS, recipient of the American Diabetes Association’s (ADA) 2014 Banting Medal for Scienfitic Achievement for his research with GLP-1s. They also speak with Jonathan Campbell, PhD, Associate Professor in Medicine at the Duke Molecular Physiology Institute at Duke University. They discuss the history of endocrine biology research and their article, “Therapeutic Targeting of the GIP Receptor—Revisiting the Controversies,” available for free at doi.org/10.2337/db25-0393.

42:00 As the conversation continues, our guests discuss the controversy of the GIP receptor agonism, antagonism debate. These arguments are highlighted in a special debate series in the August issue of Diabetes, featuring a point article, “A Contemporary Rationale for Agonism of the GIP Receptor in the Treatment of Obesity,” available for free at ​​doi.org/10.2337/dbi24-0026, and a counterpoint article titled “GIP Receptor Antagonists in the Pharmacotherapy of Obesity: Physiologic, Genetic, and Clinical Rationale,” also available for free at doi.org/10.2337/dbi24-0027.

And don’t forget to reach out! Let us know your stance in the debate between agonism and antagonism, and share your favorite science-related podcasts!

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don’t forget to smash that “follow” button!

Welcome to the July 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the July 2025 issue of Diabetes.

6:50 In the first interview segment, our hosts discuss July’s Paper of the Month, titled “Novel Cell-to-Cell Communications Between Macrophages and Fibroblasts Regulate Obesity-Induced Adipose Tissue Fibrosis.” They’re joined by corresponding authors Dr. Takayoshi Suganami, professor in the Department of Molecular Medicine and Metabolism, the Research Institute of Environmental Medicine at Nagoya University in Nagoya, Japan, and Miyako Tanaka, a lecturer in the same department. This article is available for free at doi.org/10.2337/db24-0762.

22:25 Our hosts speak with Richard M. Watanabe, PhD, Professor of Population and Public Health Sciences in the Department of Population and Public Health Sciences at the University of Southern California Keck School of Medicine. His paper, “Genetic Variations in GCKR and PNPLA3 Regulate Metabolic Balance Across the Liver,” is available at doi.org/10.2337/db24-0923.

46:50 In this month’s edition of “Sweet Talk,” our hosts are joined by Barbara B. Kahn, MD, recipient of the American Diabetes Association’s Albert Renold Distinguished Career Award, to discuss her work uncovering key molecular mechanisms contributing to type two diabetes and the role of adipose tissue in regulating systemic insulin sensitivity. Dr. Kahn is the George Richards Minot Professor of Medicine at Harvard Medical School and Vice Chair for Research Strategy at Beth Israel Deaconess Medical Center in Boston.

To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don’t forget to smash that “follow” button!