Vitiligo may show up on your skin, but the drama starts lower down — in your gut, where trillions of microbes run the show. When that microscopic circus gets out of tune, your immune system can lose its mind.

Enter sucralose — that “harmless” fake sugar in your diet soda and protein shake. It tastes sweet, promises zero calories, and might just be quietly gaslighting your gut bacteria. The result? More inflammation, less balance, and a very confused immune system.

In this episode:

• How sucralose messes with your microbiome
• Why that matters if your immune system’s already on edge
• The fine line between calming inflammation and killing defense
• And why “sugar-free” doesn’t mean consequence-free

Your gut’s a garden, not a chemistry set. Sucralose won’t nuke it overnight — but it might slowly evict the good tenants and hand the keys to the troublemakers.

Full story: Sucralose, Your Gut, and Vitiligo – Should We Worry?

From Easter Island soil to modern skin science — meet rapamycin, the molecule that might just change vitiligo care.

Once known mainly as an anti-rejection drug for organ transplants, rapamycin is now being tested as a topical treatment that could both calm the immune attack and help pigment return. Early studies look promising: minimal side effects, slow but steady repigmentation, and surprisingly good tolerance.

In this episode, we explore:

• How rapamycin rewires the skin’s immune balance
• Why it’s called both a suppressor and a rejuvenator
• What Phase II trials are revealing so far
• And whether this “longevity drug” might also restore color to the skin

It’s too early to call it a breakthrough — but this little molecule from a far-off island might just be the next quiet revolution in vitiligo therapy.

Full story: Topical Rapamycin: Could This Be Vitiligo’s Next Big Breakthrough?

Vitiligo isn’t just skin deep — it’s a full-body story. Almost half of those living with it also face anxiety or depression, tied together by the same stress circuits that link the brain and the skin.

In this episode, we dive into how antidepressants affect both body and mind — and why that matters for vitiligo care.

You’ll hear:

• How stress hormones can trigger or worsen pigment loss
• What The Lancet revealed about antidepressant side effects
• Which medications support balance without tipping the scale
• Why therapy, sleep, and lifestyle still matter more than any pill

A grounded look at the skin–brain connection — and how healing the mind can help the skin follow.

Full story: Vitiligo and Mental Health: How Antidepressants May Shape the Body