Cholestatic Pruritus Associated with PBC: Understanding Unmet Patient Needs and Treatment Strategies cover art

Cholestatic Pruritus Associated with PBC: Understanding Unmet Patient Needs and Treatment Strategies

Cholestatic Pruritus Associated with PBC: Understanding Unmet Patient Needs and Treatment Strategies

By: Annenberg Center for Health Sciences
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About this listen

 Pruritus occurs in up to 70% of patients with primary biliary cholangitis (PBC), can be severe, and lead to increased morbidity-including worsening fatigue and quality of sleep. Standard of care treatment has relied on a variety of medications with limited effectiveness and tolerability adding to the patient disease burden. Alan Bonder, MD, and Kris Kowdley, MD, discuss unmet patient needs, pruritus assessment tools, and guideline-based therapy provided by an interprofessional care team.Annenberg Center for Health Sciences Hygiene & Healthy Living Physical Illness & Disease
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Episodes
  • Interprofessional Patient Case

    Interprofessional Patient Case
    Feb 11 2025

    Alan Bonder, MD, and Kris Kowdley, MD, discuss unmet patient needs, pruritus assessment tools, and guideline-based therapy provided by an interprofessional care team. They also explore safety and efficacy data from trials of emerging treatment options including ileal bile acid transporter (IBAT) inhibitors and peroxisome proliferator-activated receptor (PPAR) agonists.
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    5 mins
  • Investigational Therapies

    Investigational Therapies
    Feb 11 2025
    Alan Bonder, MD, and Kris Kowdley, MD, discuss unmet patient needs, pruritus assessment tools, and guideline-based therapy provided by an interprofessional care team. They also explore safety and efficacy data from trials of emerging treatment options including ileal bile acid transporter (IBAT) inhibitors and peroxisome proliferator-activated receptor (PPAR) agonists.
    Show More Show Less
    5 mins
  • Current Treatment Options

    Current Treatment Options
    Feb 11 2025

    Alan Bonder, MD, and Kris Kowdley, MD, discuss unmet patient needs, pruritus assessment tools, and guideline-based therapy provided by an interprofessional care team. They also explore safety and efficacy data from trials of emerging treatment options including ileal bile acid transporter (IBAT) inhibitors and peroxisome proliferator-activated receptor (PPAR) agonists.
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    16 mins

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