Changing the Ovarian Cancer Treatment Landscape with a DNA-Mediated Immunotherapy cover art

Changing the Ovarian Cancer Treatment Landscape with a DNA-Mediated Immunotherapy

Changing the Ovarian Cancer Treatment Landscape with a DNA-Mediated Immunotherapy

Listen for free

View show details

About this listen

Ovarian cancer remains one of the deadliest cancers affecting women, and it is expected to claim nearly 13,000 lives in the United States in 2025. Despite progress in survival rates, nearly 80 percent of patients are still diagnosed at advanced stages, when the disease has already spread and is difficult to treat. Imunon’s experimental DNA-mediated immunotherapy is designed to deliver interleukin-12 directly into the tumor. A phase 2 study demonstrated that the experimental therapy, when combined with the standard of care, provided a 13-month survival benefit compared to women receiving only the standard of care. We spoke to Stacy Lindborg, CEO of Imunon, about the company’s DNA-mediated immunotherapy, how it avoids the systemic toxicities that undermined earlier IL-12 approaches, and how it could change the treatment landscape for the disease.

No reviews yet
In the spirit of reconciliation, Audible acknowledges the Traditional Custodians of country throughout Australia and their connections to land, sea and community. We pay our respect to their elders past and present and extend that respect to all Aboriginal and Torres Strait Islander peoples today.