In this episode, Dr. Bruno Fernandes acts as host alongside special guest co-host Dr. Carlos Quezada-Ruiz to welcome Dr. Rishi Singh, the newly appointed Chair of Ophthalmology at Harvard Medical School and Mass Eye and Ear, and Chair of the Integrated Department of Ophthalmology at Mass General Brigham.

Dr. Singh joins the podcast just 42 days into his new tenure to discuss the transition from the Cleveland Clinic to one of the world's most prestigious academic institutions.

Key topics in this episode include:

• The "First 90 Days" Approach: Why listening is more important than prescribing solutions when taking on a new leadership role.

• The Circuitous Career Path: How taking on "unsexy" jobs like coding and documentation can build the essential skills needed for executive leadership.

• AI Realism: Dr. Singh shares his cautious optimism regarding Artificial Intelligence, discussing why it won't solve basic logistical issues instantly and the dangers of relying on the "black box" without human oversight.

• Retina & Drug Development: A look at the logistical burdens of Wet AMD treatment, the complexities of clinical trials, and the potential (and current limitations) of gene therapy as a "Holy Grail."

• Mentorship: Why being "uncomfortable" is the best way to grow as a young ophthalmologist.

About the Guest: Dr. Rishi Singh is a vitreoretinal surgeon and physician-scientist with over 300 peer-reviewed publications. He formerly served as Vice President and Chief Medical Officer at Cleveland Clinic Martin Hospitals.

In this week’s episode of the BroadEYE Podcast, hosts Dr. Shawn Maloney and Dr. Carlos Quezada-Ruiz sit down with Dr. Wiley Chambers, recently retired Deputy Director of the Division of Ophthalmology at the U.S. Food and Drug Administration (FDA). With over 36 years at the FDA, Dr. Chambers offers a rare insider’s perspective on regulatory science, ophthalmic drug development, and the evolution of clinical trial oversight.

This episode explores:

• How ophthalmology regulation has changed over the decades
• Common pitfalls in pre-IND meetings and what smart innovators do differently
• Lessons learned from reviewing countless drug and biologic applications
• The future of FDA guidance in areas like rare disease, gene therapy, and digital endpoints

Dr. Chambers also shares personal reflections on mentorship, scientific integrity, and his transition out of federal service after a distinguished career.

About Our Guest Dr. Wiley Chambers served as a lead ophthalmic reviewer at the U.S. FDA from 1987 until his retirement in 2023. As Deputy Director of the Division of Ophthal

In this episode of the BroadEYE Podcast, we welcome inventor, researcher, and MacArthur Fellow Dr. Joshua Miele. Known for his pioneering work in accessible technology for blind users, Dr. Miele shares his journey from early advocacy to his role at Amazon’s Lab126, where he continues to develop tools that redefine independence and equity in the built and digital worlds.

Explore Dr. Joshua Miele’s work, projects, and writings on his personal site, MieleLab, which highlights his innovations in accessible design and disability inclusion. You can visit it here: www.mielelab.com

Joining as co-host is Victoria Nolan—a decorated Paralympian, accessibility advocate, and BroadEYE regular. With lived experience navigating vision loss, Victoria brings deep empathy and clarity to the discussion, drawing out the personal and systemic forces that shape accessibility work today.

Together, they explore:

• The real meaning of inclusion, and why accessibility must be baked in—not bolted on.

• Dr. Miele’s development of tactile maps, screen readers, and accessible media interfaces.

• How institutions can move from compliance to genuine cultural transformation.

Dr. Miele also reflects on the resilience required to challenge ableist assumptions and the power of disabled leadership in tech innovation. His message is clear: access is not about charity—it’s about justice.

About Our Guests

Dr. Joshua Miele is a blind scientist, designer, and advocate for accessibility. Currently a Principal Accessibility Researcher at Amazon, he has developed technologies that empower blind and visually impaired people to navigate cities, classrooms, and digital spaces. He is a 2021 MacArthur “Genius Grant” recipient and a prominent voice for disability rights and design justice.

Want to learn more? Pick up Dr. Miele’s powerful memoir, “Connecting the Dots: From the Blind Side”, now available on Amazon.

Victoria Nolan is a Canadian Paralympic rower, author, and passionate advocate for inclusion. Diagnosed with retinitis pigmentosa in her youth, she went on to compete internationally in rowing, including two Paralympic Games. Today, she is an influential public speaker and ambassador for breaking down barriers for people with vision loss.