Brain connectivity as a new target for Alzheimer's disease therapy?
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Brain connectivity as a new target for Alzheimer's disease therapy?
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About this listen
Welcome to the 34th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.
This episode features a discussion with first author Dr Lorenzo Pini of the Brain article entitled: Brain connectivity as a new target for Alzheimer's disease therapy?
We discuss a fascinating review into the literature examing brain connectivity in Alzheimer's disease as a biomarker for symptom progression, diagnosis and monitoring response to treatment. Further, they discuss whether brain stimulation to target connectivity may have therapeutic opportunities. The article also features a discussion around digital twins to facilitate Alzheimer's research - well worth a read!
Check out the full article on the Brain website as part of the Feb 2026 issue: https://doi.org/10.1093/brain/awaf404
This episode was co-hosted, edited and produced by Michael and Adam Handel, co-produced by Xin You Tai and Antonia Johnston, original music by Ammar Al-Chalabi.